CAS number; 534521
NIOSH REL: 0.2 mg/m3 TWA [skin]
Current OSHA PEL: 0.2 mg/m3 TWA [skin]
1989 OSHA PEL: Same as current PEL
1993-1994 ACGIH TLV: 0.2 mg/m3 TWA [skin]
Description of Substance: Yellow, odorless solid.
LEL:. . Unknown
Original (SCP) IDLH: 5 mg/m3
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Hunter  that 4.7 mg/m3 per day caused the following symptoms in a factory worker: fever, weight loss, a 400% rise in the basal rate of metabolism, rapid pulse, rapid respiration, profuse sweating, shortness of breath, and cough [McDonald 1943]. It is obvious that the chosen IDLH has been set conservatively, but no other quantitative data are available on which to base an IDLH.
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA
Lethal concentration data:
Lethal dose data:
Human data: An exposure of 4.7 mg/m3 per day resulted in fever, a basal metabolic rate of 400, rapid pulse and respiration, profuse sweating, shortness of breath, and cough [Fairhall 1957]. A single oral dose 75 mg produced no toxic effects in five volunteers [Harvey et al. 1951]. [Note: An oral dose of 75 mg is equivalent to a worker being exposed to 50 mg/m3 for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]
|Revised IDLH: 5 mg/m3 [Unchanged]
Basis for revised IDLH: Based on acute toxicity data in humans [Fairhall 1957; Harvey et al. 1951] and animals [Colliot 1972], the original IDLH for dinitroocresol (5 mg/m3) is not being revised at this time.
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