International Chemical Safety Cards

NITROBENZENE

ICSC: 0065

Nitrobenzol
C₆H₅NO₂
Molecular mass: 123.1

ICSC #    0065
CAS #     98-95-3
RTECS # DA6475000
UN #        1662
EC #         609-003-00-7
September 20, 1993 Peer reviewed

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION	Above 88°C explosive vapour/air mixtures may be formed. Risk of fire and explosion (see Chemical Dangers).	Above 88°C use a closed system, ventilation.	In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE		PREVENT GENERATION OF MISTS! STRICT HYGIENE!	IN ALL CASES CONSULT A DOCTOR!
•INHALATION	Headache. Blue lips or finger nails. Blue skin. Dizziness. Nausea. Weakness. Unconsciousness.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
•SKIN	MAY BE ABSORBED! (Further see Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES		Safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION		Do not eat, drink, or smoke during work.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT absorb in saw-dust or other combustible absorbents. Personal protection: complete protective clothing including self-contained breathing apparatus.

Separated from combustible and reducing substances, strong oxidants, strong acids, food and feedstuffs .

Do not transport with food and feedstuffs.
T symbol
N symbol
R: 23/24/25-40-48/23/24-51/53-62
S: 1/2-28-36/37-45-61
UN Hazard Class: 6.1
UN Packing Group: II

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0065

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

NITROBENZENE

ICSC: 0065

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PHYSICAL STATE; APPEARANCE:
PALE YELLOW OILY LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
On combustion, forms toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants reducing agents causing fire and explosion hazard. Attacks many plastics. Forms explosive (thermally unstable) substances or mixtures with many organic and inorganic compounds like oxidants, aluminium chloride with phenol, potassium hydroxide anhydrous or with small amounts of methanol, aniline with glycerol, phosphoruspentachloride, nitric acid, sulphuric acid, potassium.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004).
MAK: skin absorption (H);
Carcinogen category: 3B;
(DFG 2004).
OSHA PEL: TWA 1 ppm (5 mg/m³) skin
NIOSH REL: TWA 1 ppm (5 mg/m³) skin
NIOSH IDLH: 200 ppm

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the blood cells , resulting in formation of methaemoglobin. Exposure could cause lowering of consciousness. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood forming organs. It may have effects on the liver.

PHYSICAL
PROPERTIES

Boiling point: 211°C
Melting point: 6°C
Relative density (water = 1): 1.2
Solubility in water, g/100 ml: 0.2
Vapour pressure, Pa at 20°C: 20
Relative vapour density (air = 1): 4.2

Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 88°C c.c.
Auto-ignition temperature: 480°C
Explosive limits, vol% in air: 1.8-40
Octanol/water partition coefficient as log Pow: 1.86

ENVIRONMENTAL
DATA

N O T E S

Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Do NOT take working clothes home. On distillation, do NOT evaporate to dryness because of the explosion hazard. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification.

Transport Emergency Card: TEC (R)-61S1662
NFPA Code: H 3; F 2; R 0;

ADDITIONAL INFORMATION

ICSC: 0065	NITROBENZENE
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.