International Chemical Safety Cards IODINE ICSC: 0167 Jod Iode Iodio Yodo I2 Molecular mass: 253.8 ICSC #    0167 CAS #     7553-56-2 RTECS # NN1575000 EC #         053-001-00-3 April 22, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible but enhances combustion of other substances. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. NO contact with flammable substances. In case of fire in the surroundings: use appropriate extinguishing media. EXPLOSION EXPOSURE STRICT HYGIENE!  •INHALATION Cough. Wheezing. Laboured breathing. Symptoms may be delayed (see Notes). Ventilation (not if powder), local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Redness. Pain. Protective gloves. Protective clothing. First rinse with plenty of water, then remove contaminated clothes and rinse again.  •EYES Causes watering of the eyes. Redness. Pain. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Diarrhoea. Nausea. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT let this chemical enter the environment. Personal protection: filter respirator for inorganic gases, vapours and halogens. Separated from incompatible materials . See Chemical Dangers. Well closed. Ventilation along the floor. Xn symbol N symbol R: 20/21-50 S: 2-23-25-61 SEE IMPORTANT INFORMATION ON BACK ICSC: 0167 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards IODINE ICSC: 0167 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: BLUISH BLACK OR DARK PURPLE CRYSTALS , WITH PUNGENT ODOUR. PHYSICAL DANGERS: Iodine readily sublimes. CHEMICAL DANGERS: Upon heating, toxic fumes are formed. The substance is a strong oxidant and reacts with combustible and reducing materials. Reacts violently with metal powders, antimony, ammonia, acetaldehyde, acetylene causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.1 ppm; (Ceiling value); (ACGIH 2004). MAK: 0.1 ppm, 1.1 mg/m³; Peak limitation category: I(I); (DFG 2003). OSHA PEL: C 0.1 ppm (1 mg/m3) NIOSH REL: C 0.1 ppm (1 mg/m3) NIOSH IDLH: 2 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: Lachrymation. The substance is severely irritating to the eyes and the respiratory tract , and is irritating to the skin . Inhalation of the vapour may cause asthma-like reactions (RADS). Inhalation of the vapour may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization in rare cases. Repeated or prolonged inhalation exposure may cause asthma-like syndrome (RADS). The substance may have effects on the thyroid. PHYSICAL PROPERTIES Boiling point: 184°C Melting point: 114°C Relative density (water = 1): 4.9 Solubility in water, g/100 ml at 20°C: 0.03 Vapour pressure, kPa at 25°C: 0.04 Relative vapour density (air = 1): 8.8 Relative density of the vapour/air-mixture at 20°C (air = 1): 1 Octanol/water partition coefficient as log Pow: 2.49 ENVIRONMENTAL DATA This substance may be hazardous in the environment; special attention should be given to fish. N O T E S The occupational exposure limit value should not be exceeded during any part of the working exposure. Rinse contaminated clothes (fire hazard) with plenty of water. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. ADDITIONAL INFORMATION ICSC: 0167 IODINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.