International Chemical Safety Cards TRIMELLITIC ANHYDRIDE ICSC: 0345 1,2,4-Benzenetricarboxylic anhydride 1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic acid C9H4O5 Molecular mass: 192.2 ICSC #    0345 CAS #     552-30-7 RTECS # DC2050000 EC #         607-097-00-4 April 22, 1994 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Water spray, powder. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent build-up of electrostatic charges (e.g., by grounding). Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Cough. Dizziness. Wheezing. Chills. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Redness. Pain. Safety spectacles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder. (Extra personal protection: P2 filter respirator for harmful particles). Separated from strong oxidants. Dry. Xn symbol R: 36/37/38-42 S: 2-22-28 SEE IMPORTANT INFORMATION ON BACK ICSC: 0345 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards TRIMELLITIC ANHYDRIDE ICSC: 0345 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS, ODOURLESS CRYSTALS OR POWDER. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. CHEMICAL DANGERS: Reacts violently with oxidants. Reacts slowly with water to form trimellitic acid. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.005 ppm; 0.04 mg/m3 (ACGIH 1992-1993). OSHA PEL: none NIOSH REL: TWA 0.005 ppm (0.04 mg/m3) Should be handled in the workplace as an extremely toxic substance. NIOSH IDLH: No data ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. Inhalation of the powder or vapour may cause asthmatic reactions (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged inhalation exposure may cause asthma. Lungs may be affected by repeated or prolonged exposure. The substance may have effects on the blood , resulting in anaemia (see Notes). PHYSICAL PROPERTIES Boiling point: 240-245°C Melting point: 161-163.5°C Solubility in water: reaction Vapour pressure, kPa at 25°C: <0.01 ENVIRONMENTAL DATA N O T E S The substance is combustible but no flash point is available in literature. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. ADDITIONAL INFORMATION ICSC: 0345 TRIMELLITIC ANHYDRIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.