International Chemical Safety Cards 2,4-XYLENOL ICSC: 0458 2,4-Dimethylphenol m-Xylenol 1-Hydroxy-2.4-dimethylbenzene C8H10O / (CH3)2C6H3OH Molecular mass: 122.17 ICSC #    0458 CAS #     105-67-9 RTECS # ZE5600000 UN #        2261 EC #         604-006-00-X May 07, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! PREVENT GENERATION OF MISTS! STRICT HYGIENE!  •INHALATION Burning sensation. Cough. Sore throat. Shortness of breath. See Notes. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Redness. Pain. Skin burns. Protective clothing. Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Redness. Pain. Severe deep burns. Safety goggles, face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal pain. Nausea. Vomiting. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. If liquid: Collect leaking liquid in covered plastic containers. Do NOT let this chemical enter the environment. Chemical protection suit including self-contained breathing apparatus. Separated from food and feedstuffs , acid anhydrides , acid chlorides , bases and oxidants . Do not transport with food and feedstuffs. Marine pollutant. Note: C T symbol N symbol R: 24/25-34-51/53 S: 1/2-26-36/37/39-45-51 UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0458 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2,4-XYLENOL ICSC: 0458 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: YELLOW TO BROWN LIQUID OR COLOURLESS CRYSTALS . PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic gases and irritating fumes . Reacts with acid anhydrides , acid chlorides , bases , oxidants . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, by ingestion and through the skin. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the skin the respiratory tract and the eyes. Corrosive on ingestion. Inhalation of an aerosol of this substance may cause lung oedema (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. PHYSICAL PROPERTIES Boiling point: 211.5°C Melting point: 25.4-26°C Density: 0.97 g/cm3 Solubility in water, g/100 ml at 25°C: 0.79 Vapour pressure, Pa at 20°C: 8 Flash point: >112°C c.c. Auto-ignition temperature: 599°C Explosive limits, vol% in air: 1.1-6.4 Octanol/water partition coefficient as log Pow: 2.3 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. N O T E S The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. NFPA Code: H2; F1; R; 0 Transport Emergency Card: TEC (R)-61GT1-II ADDITIONAL INFORMATION ICSC: 0458 2,4-XYLENOL (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.