International Chemical Safety Cards

EPN

ICSC: 0753

Phosphonothioic acid, phenyl-, O-ethyl O-(4-nitrophenyl) ester
O-Ethyl O-4-nitrophenyl phenyl phosphonothioate
C₁₄H₁₄NO₄PS
Molecular mass: 323.3

ICSC #    0753
CAS #     2104-64-5
RTECS # TB1925000
UN #        2783
EC #         015-036-00-2
March 26, 1998 Peer reviewed

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION

EXPOSURE		STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!	IN ALL CASES CONSULT A DOCTOR!
•INHALATION	Headache. Wheezing. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Convulsions. Unconsciousness. Symptoms may be delayed (see Notes).	Local exhaust or breathing protection.	Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
•SKIN	MAY BE ABSORBED! Burning sensation. (See Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
•EYES	Blurred vision.	Face shield, or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION	Nausea. Abdominal cramps. Vomiting. Diarrhoea. Laboured breathing. (Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Do NOT wash away into sewer. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Chemical protection suit including self-contained breathing apparatus.

Separated from food and feedstuffs. Well closed.

Do not transport with food and feedstuffs.
Severe marine pollutant.
T+ symbol
N symbol
R: 27/28-50/53
S: 1/2-22-36/37-45-60-61
UN Hazard Class: 6.1
UN Packing Group: I

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0753

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

EPN

ICSC: 0753

I

M

P

O

R

T

A

N

T

D

A

T

A

PHYSICAL STATE; APPEARANCE:
YELLOW TO BROWN CRYSTALLINE POWDER , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes including nitrogen oxides, phosphorous oxides, sulfur oxides. Reacts with oxidants. The substance decomposes under influence of alkalies (hydrolysis) forming p-nitrophenol (see ICSC 0066).

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.1 mg/m³ (as TWA) (skin) (ACGIH 1997).
MAK: 0.5 mg/m³; III, H (1996).
OSHA PEL: TWA 0.5 mg/m³ skin
NIOSH REL: TWA 0.5 mg/m³ skin
NIOSH IDLH: 5 mg/m³

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure may result in unconsciousness or death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL
PROPERTIES

Melting point: 36°C
Density: 1.3 g/cm3
Solubility in water: none

Vapour pressure, Pa at 25°C: < 0.01
Octanol/water partition coefficient as log Pow: > 5.02

ENVIRONMENTAL
DATA

The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to honey bees. Avoid release to the environment in circumstances different to normal use.

N O T E S

Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until 30 minutes to 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home.

Transport Emergency Card: TEC (R)-61G41a

ADDITIONAL INFORMATION

ICSC: 0753	EPN
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.