International Chemical Safety Cards CHLORMEQUAT CHLORIDE ICSC: 0781 (2-Chloroethyl)trimethylammonium chloride 2-Chloro-N,N,N-trimethylethanaminium chloride Chlorocholine chloride (ClCH2CH2N(CH3)3)Cl / C5H13Cl2N Molecular mass: 158.1 ICSC #    0781 CAS #     999-81-5 RTECS # BP5250000 EC #         007-003-00-6 April 12, 2000 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  •INHALATION (See Ingestion). Local exhaust or breathing protection. Fresh air, rest.  •SKIN MAY BE ABSORBED! Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Excessive salivation. Sweating. Visual disturbance. Diarrhoea. Dizziness. Headache. Laboured breathing. Nausea. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: P2 filter respirator for harmful particles). Dry. Keep in a well-ventilated room. In glass, high-density plastic, rubber or epoxy resin-protected metal containers. Xn symbol R: 21/22 S: 2-36/37 SEE IMPORTANT INFORMATION ON BACK ICSC: 0781 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards CHLORMEQUAT CHLORIDE ICSC: 0781 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO WHITE EXTREMELY HYGROSCOPIC CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic and corrosive fumes including nitrogen oxides , hydrogen chloride . The substance decomposes on heating with strong aqueous alkali solutions producing trimethylamine and other gaseous products. Attacks many metals in presence of water. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly by dispersion. EFFECTS OF SHORT-TERM EXPOSURE: The aerosol of this substance irritates slightly the eyes. The substance may cause effects on the nervous system: cholinergic symptoms without acetylcholinesterase inhibition (see notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Melting point (decomposes): 245°C Solubility in water: good (74 g/100 ml at 20°C) Vapour pressure, Pa at 20°C: negligible ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. Avoid release to the environment in circumstances different to normal use. N O T E S Use of atropine as specific treatment is contraindicated. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. ADDITIONAL INFORMATION ICSC: 0781 CHLORMEQUAT CHLORIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.