International Chemical Safety Cards LEAD TETROXIDE ICSC: 1002 Lead orthoplumbate Red lead Minium C.I. Pigment Red 105 Pb3O4 Molecular mass: 685.6 ICSC #    1002 CAS #     1314-41-6 RTECS # OG5425000 EC #         082-001-00-6 October 15, 2001 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Gives off irritating or toxic fumes (or gases) in a fire. Many reactions may cause fire or explosion. NO contact with reducing agents. In case of fire in the surroundings: water spray. EXPLOSION EXPOSURE AVOID EXPOSURE OF (PREGNANT) WOMEN!  •INHALATION Local exhaust or breathing protection. Fresh air, rest.  •SKIN Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. Personal protection: P3 filter respirator for toxic particles. Separated from food and feedstuffs and strong reducing agents. See Chemical Dangers. T symbol N symbol R: 61-20/22-33-62-50/53 S: 53-45-60-61 SEE IMPORTANT INFORMATION ON BACK ICSC: 1002 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards LEAD TETROXIDE ICSC: 1002 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: RED CRYSTALS OR POWDER. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing oxygen and toxic fumes. Reacts violently with reducing agents causing fire hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: (as Pb) 0.05 mg/m³ as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004). MAK: (as Pb) (Inhalable fraction); Carcinogen category: 3B; Germ cell mutagen group: 3A; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood , bone marrow , central nervous system , peripheral nervous system and kidneys , resulting in anaemia, encephalopathy (e.g., convulsions), peripheral nerve disease, abdominal cramps and kidney impairment. Causes toxicity to human reproduction or development. PHYSICAL PROPERTIES Melting point (decomposes): 500°C Density: 9.1 g/cm3 Solubility in water: none ENVIRONMENTAL DATA Bioaccumulation of this chemical may occur in plants and in mammals. It is strongly advised that this substance does not enter the environment. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. Card has been partly updated in April 2005. See section Occupational Exposure Limits. ADDITIONAL INFORMATION ICSC: 1002 LEAD TETROXIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.