International Chemical Safety Cards PERFLUOROISOBUTYLENE ICSC: 1216 Octafluoroisobutylene 1,1,3,3,3-Pentafluoro-2-trifluoromethyl-1-propene Octafluoro-sec-butene C4F8 Molecular mass: 200.0 ICSC #    1216 CAS #     382-21-8 RTECS # UD1800000 April 21, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE In case of fire in the surroundings: use appropriate extinguishing media. EXPLOSION EXPOSURE STRICT HYGIENE!  •INHALATION Sore throat. Cough. Nausea. Headache. Weakness. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Protective gloves.  •EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Personal protection: self-contained breathing apparatus. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1216 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards PERFLUOROISOBUTYLENE ICSC: 1216 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS GAS. PHYSICAL DANGERS: CHEMICAL DANGERS: OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.01 ppm; (Ceiling value); (ACGIH 2004). MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful concentration of this gas in the air will be reached very quickly on loss of containment. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the respiratory tract . Inhalation of this gas may cause lung oedema (see Notes). Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 7°C Density: 1.6 g/l ENVIRONMENTAL DATA N O T E S This substance is formed as a by-product in tetrafluoroethylene production and during thermal degradation of polytetrafluoroethylene (PTFE/Teflon(R)) at approximately 425°C. The occupational exposure limit value should not be exceeded during any part of the working exposure. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Card has been partly updated in April 2005. See section Notes. ADDITIONAL INFORMATION ICSC: 1216 PERFLUOROISOBUTYLENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.