International Chemical Safety Cards HEXAMETHYLENETETRAMINE ICSC: 1228 1,3,5,7-Tetraazaadamantane Methenamine Hexamine 1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7))decane C6H12N4 Molecular mass: 140.2 ICSC #    1228 CAS #     100-97-0 RTECS # MN4725000 UN #        1328 EC #         612-101-00-2 March 08, 2002 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Foam, water spray, powder. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION Cough. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. Personal protection: A/P2 filter respirator for organic vapour and harmful dust. Separated from strong acids and strong oxidants. Dry. F symbol Xn symbol R: 11-42/43 S: 2-16-22-24-37 UN Hazard Class: 4.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 1228 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards HEXAMETHYLENETETRAMINE ICSC: 1228 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: HYGROSCOPIC , COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. CHEMICAL DANGERS: The substance decomposes on heating or on burning producing toxic and corrosive gasesincluding formaldehyde,ammonia,hydrogen cyanide and nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants and strong acids producing toxic and corrosive gases . Attacks aluminium and zinc. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK: IIb (not established but data is available); sensitization of skin (Sh); (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance is mildly irritating to the eyes and the skin . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma. PHYSICAL PROPERTIES Sublimation point: about 260°C Density: 1.33 g/cm3 Solubility in water: good Relative vapour density (air = 1): 4.9 Flash point: 250°C c.c. Auto-ignition temperature: 390°C Octanol/water partition coefficient as log Pow: -2.84 ENVIRONMENTAL DATA N O T E S The substance may release formaldehyde. See ICSC 0695 Formaldehyde. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response. Transport Emergency Card: TEC (R)-41S1328 ADDITIONAL INFORMATION ICSC: 1228 HEXAMETHYLENETETRAMINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.