International Chemical Safety Cards BROMUCONAZOLE ICSC: 1264 1-((2RS,4RS2RS,4SR)-4-Bromo-2-(2,4-dichlorophenyl)tetrahydrofurfuryl)-1H-1,2,4-triazole 1-((4-Bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl)methyl)-1H-1,2,4-triazole C13H12BrCl2N3O Molecular mass: 377.1 ICSC #    1264 CAS #     116255-48-2 RTECS # XZ4130000 October 26, 1995 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION See Notes. Avoid inhalation of fine dust and mist. Local exhaust or breathing protection. Fresh air, rest.  •SKIN Protective gloves. Rinse and then wash skin with water and soap.  •EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION See Notes. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Rest. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P2 filter respirator for harmful particles). Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Do not transport with food and feedstuffs. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1264 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards BROMUCONAZOLE ICSC: 1264 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS, COLOURLESS CRYSTALS OR POWDER. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic gases/fumes including nitrogen oxides, hydrogen chloride, hydrogen bromide, carbon monoxide. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system, if ingested , resulting in depression. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver , resulting in tissue lesions and impaired functions. PHYSICAL PROPERTIES Melting point: 84°C Relative density (water = 1): 1.7 Solubility in water, g/100 ml: 0.05 Vapour pressure, Pa at 25°C: negligible Octanol/water partition coefficient as log Pow: 3.12-3.48 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. N O T E S Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Granit is a trade name. ADDITIONAL INFORMATION ICSC: 1264 BROMUCONAZOLE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.