International Chemical Safety Cards 4-CHLOROTOLUENE ICSC: 1386 p-Chlorotoluene 1-Chloro-4-methylbenzene p-Tolyl chloride C7H7Cl Molecular mass: 126.6 ICSC #    1386 CAS #     106-43-4 RTECS # XS9010000 UN #        2238 EC #         602-040-00-X March 14, 2001 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Powder, AFFF, foam, carbon dioxide. EXPLOSION Above 49°C explosive vapour/air mixtures may be formed. Above 49°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE  •INHALATION Ventilation, local exhaust, or breathing protection. Fresh air, rest.  •SKIN Dry skin. Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. (Extra personal protection: filter respirator for organic gases and vapours.) Fireproof. Separated from strong oxidants. Marine pollutant. Note: C Xn symbol N symbol R: 20-51/53 S: 2-24/25-61 UN Hazard Class: 3 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 1386 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 4-CHLOROTOLUENE ICSC: 1386 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: On combustion, forms toxic gases including carbon monoxide , hydrogen chloride , possibly phosgene . Reacts with strong oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: EFFECTS OF SHORT-TERM EXPOSURE: Swallowing the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The liquid defats the skin. PHYSICAL PROPERTIES Boiling point: 162°C Melting point: 7.5°C Relative density (water = 1): 1.07 Solubility in water, g/100 ml at 20°C: 0.01 Vapour pressure, kPa at 20°C: 0.35 Relative vapour density (air = 1): 4.4 Flash point: 49°C Auto-ignition temperature: 595°C Explosive limits, vol% in air: 0.7-12.2 Octanol/water partition coefficient as log Pow: 3.33 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. N O T E S Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. Transport Emergency Card: TEC (R)-30G35c NFPA Code: H2; F2; R0; ADDITIONAL INFORMATION ICSC: 1386 4-CHLOROTOLUENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.