NIOSH Pocket Guide to Chemical Hazards


CAS 2425-06-1


RTECS GW4900000
Synonyms & Trade Names
Captofol; Difolatan®; N-((1,1,2,2-Tetrachloroethyl)thio)-4-cyclohexene-1,2-dicarboximide
DOT ID & Guide


NIOSH REL: Ca TWA 0.1 mg/m3 [skin] See Appendix A
OSHA PEL†: none
IDLH Ca [N.D.] See: IDLH INDEX Conversion
Physical Description
White, crystalline solid with a slight, characteristic pungent odor. [fungicide] [Note: Available commercially as a wettable powder or in liquid form.]
MW: 349.1
BP: Decomposes
MLT: 321°F (Decomposes)
Sol: 0.0001%
VP: 0.000008 mmHg
Sp.Gr: ?

Fl.P: NA

Noncombustible Solid, but may be dissolved in flammable liquids.
Incompatibilities & Reactivities
Acids, acid vapors, strong oxidizers
Measurement Methods
NIOSH 0500
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, respiratory system; dermatitis, skin sensitization; conjunctivitis; bronchitis, wheezing; diarrhea, vomiting; liver, kidney injury; high blood pressure; in animals: teratogenic effects; [potential occupational carcinogen]
Target Organs Eyes, skin, respiratory system, central nervous system, liver, kidneys, cardiovascular system

Cancer Site [in animals: tumors at many sites]
See also: INTRODUCTION   See ICSC CARD: 0119