NIOSH Pocket Guide to Chemical Hazards

Ethyl chloride

CAS 75-00-3


RTECS KH7525000
Synonyms & Trade Names
Chloroethane, Hydrochloric ether, Monochloroethane, Muriatic ether
DOT ID & Guide
1037 115


NIOSH REL: Handle with caution in the workplace. See Appendix C (Chloroethanes)
OSHA PEL: TWA 1000 ppm (2600 mg/m3)
IDLH 3800 ppm [10%LEL] See: 75003 Conversion 1 ppm = 2.64 mg/m3
Physical Description
Colorless gas or liquid (below 54°F) with a pungent, ether-like odor. [Note: Shipped as a liquefied compressed gas.]
MW: 64.5
BP: 54°F
FRZ: -218°F
Sol: 0.6%
VP: 1000 mmHg
IP: 10.97 eV
RGasD: 2.23
Sp.Gr: 0.92 (Liquid at 32°F)
Fl.P: NA (Gas) -58°F (Liquid)
UEL: 15.4%
LEL: 3.8%

Flammable Gas
Incompatibilities & Reactivities
Chemically-active metals such as sodium, potassium, calcium, powdered aluminum, zinc & magnesium; oxidizers; water or steam [Note: Reacts with water to form hydrochloric acid.]
Measurement Methods
NIOSH 2519
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact (liquid)
Eyes: Prevent eye contact (liquid)
Wash skin: No recommendation
Remove: When wet (flammable)
Change: No recommendation

First Aid (See procedures)
Eye: Irrigate immediately (liquid)
Skin: Water flush promptly (liquid)
Breathing: Respiratory support
Swallow: Medical attention immediately (liquid)
Important additional information about respirator selection
Respirator Recommendations OSHA
Up to 3800 ppm:
(APF = 10) Any supplied-air respirator*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption (liquid), ingestion (liquid), skin and/or eye contact
Symptoms Incoordination, inebriation; abdominal cramps; cardiac arrhythmias, cardiac arrest; liver, kidney damage
Target Organs Liver, kidneys, respiratory system, cardiovascular system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0132