NIOSH Pocket Guide to Chemical Hazards


CAS 101-77-9


RTECS BY5425000
Synonyms & Trade Names
4,4'-Diaminodiphenylmethane; para, para'-Diaminodiphenyl-methane; Dianilinomethane; 4,4'-Diphenylmethanediamine; MDA
DOT ID & Guide


NIOSH REL: Ca See Appendix A
OSHA PEL: [1910.1050] TWA 0.010 ppm ST 0.100 ppm
IDLH Ca [N.D.] See: IDLH INDEX Conversion
Physical Description
Pale-brown, crystalline solid with a faint, amine-like odor.
MW: 198.3
BP: 748°F
MLT: 198°F
Sol: 0.1%
VP(77°F): 0.0000002 mmHg
IP: 10.70 eV

Sp.Gr: 1.06 (Liquid at 212°F)
Fl.P: 374°F
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 5029
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations (See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes; jaundice, hepatitis; myocardial damage; in animals: heart, liver, spleen damage; [potential occupational carcinogen]
Target Organs Eyes, liver, cardiovascular system, spleen

Cancer Site [in animals: bladder cancer]
See also: INTRODUCTION   See ICSC CARD: 1111   See MEDICAL TESTS: 0250