NIOSH Pocket Guide to Chemical Hazards

Propylene dichloride

CAS 78-87-5


RTECS TX9625000
Synonyms & Trade Names
Dichloro-1,2-propane; 1,2-Dichloropropane
DOT ID & Guide
1279 130


NIOSH REL: Ca See Appendix A
OSHA PEL: TWA 75 ppm (350 mg/m3)
IDLH Ca [400 ppm] See: 78875 Conversion 1 ppm = 4.62 mg/m3
Physical Description
Colorless liquid with a chloroform-like odor. [pesticide]
MW: 113.0
BP: 206°F
FRZ: -149°F
Sol: 0.3%
VP: 40 mmHg
IP: 10.87 eV

Sp.Gr: 1.16
Fl.P: 60°F
UEL: 14.5%
LEL: 3.4%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids, active metals
Measurement Methods
NIOSH 1013; OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, respiratory system; drowsiness, dizziness; liver, kidney damage; in animals: central nervous system depression; [potential occupational carcinogen]
Target Organs Eyes, skin, respiratory system, liver, kidneys, central nervous system

Cancer Site [in animals: liver & mammary gland tumors]
See also: INTRODUCTION   See ICSC CARD: 0441