The Registry of Toxic Effects of Chemical Substances

Acetic acid, chloro - , sodium salt

RTECS #: AG1400000

CAS #: 3926-62-3


UPDATE: October 1997 MW: 116.48 MF: C2H2ClO2•Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. Chloroacetic acid sodium salt
  2. Chloroctan sodny (Czech)
  3. Dow defoliant
  4. Monoxone
  1. SMA
  2. SMCA
  3. Sodium monochloracetate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
guinea pig
lethal dose (50 percent kill): 115 mg/kg N/R GTPZAB 31(12),53,1987
oral
domestic bird
lowest published lethal dose: 100 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Coma

Gastrointestinal: Other changes
APTOA6 18,179,1961
oral
chicken
lethal dose (50 percent kill): 81 mg/kg N/R PCOC** -,1047,1966
oral
guinea pig
lethal dose (50 percent kill): 99 mg/kg N/R JIHTAB 23,78,1941
oral
mammal (species unspecified)
lowest published lethal dose: 150 mg/kg Behavioral: Muscle contraction or spasticity

Gastrointestinal: Hypermotility, diarrhea

Lung, Thorax, or Respiration: Dyspnea
NVTMAF 13,271,1961
oral
mouse
lethal dose (50 percent kill): 165 mg/kg N/R JPETAB 86,336,1946
oral
rat
lethal dose (50 percent kill): 95 mg/kg N/R JIHTAB 23,78,1941
oral
rabbit
lethal dose (50 percent kill): 156 mg/kg N/R PCOC** -,1047,1966


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 5,400 mg/kg/90 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Blood: Changes in leukocyte (WBC) count
TXCYAC 67,171,1991


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for control of a wide range of annual weeds in seedling stage
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NVTMAF Nordisk Veterinaermedicin Danske Udgave. (Copenhagen, Denmark)
PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS)
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-

Used for control of a wide range of annual weeds in seedling stage

RTECS Compound Description:
   Agricultural Chemical

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