The Registry of Toxic Effects of Chemical Substances

Aluminum phosphide

RTECS #: BD1400000

CAS #: 20859-73-8

UPDATE: May 2004 MW: 57.95 MF: AlP


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Aluminium phosphide (AlP)
  2. AL - Phos
  3. Aluminium fosfide (Dutch)
  4. Aluminum monophosphide
  5. Celphide
  6. Celphine
  7. Celphos
  8. Delicia
  9. Delicia gastoxin
  10. Detia
  1. Detia - Ex - B
  2. Detia gas Ex - B
  3. Fosfuri di alluminio (Italian)
  4. Fumitoxin
  5. Gastion
  6. Phosphures d'alumium (French)
  7. Phostoxin
  8. Quickphos
  9. RCRA waste number P006


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
man 		lowest published lethal concentration: 2,800 mg/m3 N/R 85ARAE 3,38,1976/1977
oral
human 		lowest published toxic dose: 85.71 mg/kg Vascular: BP lowering not characterized in autonomic section

Kidney, Ureter, and Bladder: Urine volume decreased or anuria

Blood: Methemoglobinemia- Carboxhemoglobinemia 		AJEMEN 20,130,2002
oral
man 		lowest published toxic dose: 21 mg/kg Vascular: Other changes

Gastrointestinal: Gastritis 		HUTODJ 7,343,1988
oral
man 		lowest published lethal dose: 86 mg/kg Behavioral: Coma

Vascular: Other changes

Gastrointestinal: Nausea or vomiting 		HUTODJ 7,343,1988
oral
rat 		lowest published toxic dose: 10 mg/kg Lung, Thorax, or Respiration: Respiratory depression

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		CYLPDN 22,37,2001
oral
rat 		lowest published toxic dose: 12.5 mg/kg Cardiac: EKG changes not diagnostic of above

Cardiac: Pulse rate decreased with fall in BP

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		CYLPDN 22,298,2001
oral
woman 		lowest published toxic dose: 60 mg/kg Vascular: Other changes

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Gastritis 		HUTODJ 7,343,1988
oral
woman 		lowest published lethal dose: 180 mg/kg Cardiac: Pulse rate increased without fall in BP

Liver: Jaundice, other or unclassified

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) 		HUTODJ 7,343,1988


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 mg(Al)/m3 DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,84,1998
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM LTEL 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 2 mg(Al)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 2 mg(Al)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84460;
Number of Industries 1;
Total Number of Facilities 280;
Number of Occupations 2;
Total Number of Employees Exposed 12,600
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84460;
Number of Industries 3;
Total Number of Facilities 190;
Number of Occupations 4;
Total Number of Employees Exposed 623


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a source of PHOSPHINE, in semiconductor research and as a fumigant
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE
85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision
AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983-
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

Used as a source of PHOSPHINE, in semiconductor research and as a fumigant

NIOSH PROFILE (GRAIN HANDLERS), SRI, 2/77

RTECS Compound Description:
   Agricultural Chemical
   Drug
   Human Data

ALT CAS #: 1302-45-0
ALT CAS #: 71751-04-7
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