The Registry of Toxic Effects of Chemical Substances

Barium chloride, dihydrate

RTECS #: CQ8751000

CAS #: 10326-27-9

UPDATE: November 2004 MW: 244.28 MF: BaCl2•2H2O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Barium dichloride dihydrate
  1. NCI - C61074


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 51 mg/kg N/R TXAPA9 63,461,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 47 gm/kg/13 week- continuous Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		FAATDF 19,527,1992
oral
mouse 		lowest published toxic dose: 1,868 mg/kg/15 day- continuous Liver: Changes in liver weight NTPTR* NTP-TR-432,1994
oral
rat 		lowest published toxic dose: 16 gm/kg/13 week- continuous Kidney, Ureter, and Bladder: Changes in bladder weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Nutritional and Gross Metabolic: Changes in: P 		FAATDF 19,527,1992


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg(Ba)/m3 DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as a human carcinogen DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Ba)/m3 DTLVS* 3,21,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.5 mg(Ba)/m3, MAC(short term exposure limit) 1.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - SWEDEN time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.4 mg(Ba)/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as a human carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as a human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7401;
Number of Industries 3;
Total Number of Facilities 42;
Number of Occupations 3;
Total Number of Employees Exposed 320


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NCI Carcinogenesis Studies (water);no evidence:mouse,rat


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Tumorigen

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