The Registry of Toxic Effects of Chemical Substances

Barium (II) nitrate (1:2)

RTECS #: CQ9625000

CAS #: 10022-31-8


UPDATE: November 2004 MW: 261.36 MF: N2O6•Ba


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Barium dinitrate
  2. Dusicnan barnaty (Czech)
  1. Nitrate de baryum (French)
  2. Nitric acid, barium salt


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
100 mg/24 hour moderate 28ZPAK -,10,1972
skin
rabbit
500 mg/24 hour mild 28ZPAK -,10,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 293 mg/kg Autonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
intraperitoneal
rat
lethal dose (50 percent kill): 293 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
intravenous
mouse
lethal dose (50 percent kill): 16 mg/kg N/R TXAPA9 22,150,1972
oral
dog
lowest published lethal dose: 800 mg/kg N/R YKYUA6 31,1247,1980
oral
mammal (species unspecified)
lethal dose (50 percent kill): 390 mg/kg Autonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
oral
man
lowest published toxic dose: 83 mg/kg Peripheral Nerve and Sensation: Paresthesia

Behavioral: Muscle weakness

Nutritional and Gross Metabolic: Changes in: K
JTCTDW 38,254,2000
oral
mouse
lethal dose (50 percent kill): 266 mg/kg N/R EVHPAZ 106(Suppl 2),497,1998
oral
rat
lethal dose (50 percent kill): 355 mg/kg N/R 28ZPAK -,10,1972
oral
rat
lethal dose (50 percent kill): 390 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
oral
rabbit
lowest published lethal dose: 150 mg/kg N/R YKYUA6 31,1247,1980
parenteral
rabbit
lowest published lethal dose: 30 mg/kg Gastrointestinal: Hypermotility, diarrhea

Kidney, Ureter, and Bladder: Urine volume increased
MELAAD 30,44,1939
subcutaneous
mouse
lowest published lethal dose: 10 mg/kg N/R NTIS** AEC-TR-6710


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg(Ba)/m3 DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as a human carcinogen DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Ba)/m3 DTLVS* 3,21,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - POLAND time-weighted average 0.5 mg(Ba)/m3, short term exposure limit 1.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 0.5 mg/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.4 mg(Ba)/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as a human carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as a human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 81720;
Number of Industries 12;
Total Number of Facilities 542;
Number of Occupations 13;
Total Number of Employees Exposed 2,705
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 81720;
Number of Industries 23;
Total Number of Facilities 600;
Number of Occupations 26;
Total Number of Employees Exposed 19,320;
Total Number of Female Employees Exposed 5,165


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
MELAAD Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122 Milan, Italy) V.16- 1925-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used to make BaO2, in green fire pyrotechnics, signal lights, vacuum tube industry

NIOSH PROFILE (BARIUM and ITS COMPOUNDS), SRI, 2/77

RTECS Compound Description:
   Human Data
   Primary Irritant

Click Here for Additional Information about RTECS