The Registry of Toxic Effects of Chemical Substances

1H - 2,1,3 - Benzothiadiazin - 4 (3H) - one, 3 - isopropyl - , 2,2 - dioxide

RTECS #: DK9900000

CAS #: 25057-89-0

UPDATE: August 2004 MW: 240.30 MF: C10H12N2O3S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. ACUTE TOXICITY DATA:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. BAS 3510
  2. Basagran
  3. BAS 351 - H
  4. BAS 3510H
  5. BAS 3512H
  6. BAS 3517H
  7. BAS 351 - 07H
  8. Bendioxide
  1. Bentazon
  2. Bentazone
  3. 3 - Isopropyl - 2,1,3 - benzothiadiazinon - (4) - 2,2 - dioxid (German)
  4. 3 - Isopropyl - 1H - 2,1,3 - benzothiadiazin - 4 (3H) - one - 2,2 - dioxide
  5. 3 - (1 - Methylethyl) - 1H - 2,1,3 - benzothiazain - 4 (3H) - one, 2,2 - dioxide
  6. Pledge
  7. Pentazone


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
specific locus test oral
Drosophila melanogaster 		2 mmol/L MUREAV 557,53,2004


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 25 mg/kg (6 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system 		AXVMAW 42,261,1988
oral
rat 		lowest published toxic dose: 25 mg/kg (6 day pregnant) Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive) AXVMAW 42,261,1988


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 5,100 mg/m3/4 hour N/R PEMNDP 9,65,1991
oral
cat 		lethal dose (50 percent kill): 500 mg/kg N/R GUCHAZ 6,36,1973
oral
duck 		lethal dose (50 percent kill): 15 gm/kg N/R DEVEAA 27,78,1973
oral
dog 		lethal dose (50 percent kill): 450 mg/kg N/R PSSCBG 3,242a,1972
oral
mouse 		lethal dose (50 percent kill): 1,130 mg/kg N/R YKYUA6 37,319,1986
oral
quail 		lethal dose (50 percent kill): 720 mg/kg N/R GUCHAZ 6,36,1973
oral
rat 		lethal dose (50 percent kill): 1,100 mg/kg N/R GUCHAZ 6,36,1973
oral
rabbit 		lethal dose (50 percent kill): 750 mg/kg N/R 85DPAN -,-,1971/1976
parenteral
rat 		lethal dose (50 percent kill): 1,100 mg/kg N/R DEVEAA 26,5,1972
skin
rat 		lethal dose (50 percent kill): 2,500 mg/kg N/R 85DPAN -,-,1971/1976


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for selective postemergence control of many troublesome broadleaf weeds
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE
85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976
AXVMAW Archiv fuer Experimentelle Veterinaermedizin. (S. Hirzel Verlag, Postfach 506, Leipzig DDR-7010, Ger. Dem. Rep.) V.6- 1952-
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947-
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada)
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
PSSCBG Pesticide Science. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1970-
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used for selective postemergence control of many troublesome broadleaf weeds

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Reproductive Effector

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