The Registry of Toxic Effects of Chemical Substances

Cotton dust

RTECS #: GN2275000

CAS #: N/R

UPDATE: November 2004 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. REFERENCES:

SYNONYMS:

  1. Cotton dust (ACGIH)
  2. Cotton dust, raw
  1. Cotton dust, raw (OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lowest published toxic concentration: 2 mg/m3/6 hour Lung, Thorax, or Respiration: Respiratory depression VCVPS* -,212,1998
inhalation
human 		lowest published toxic concentration: 10,000 mg/m3/10 year Lung, Thorax, or Respiration: Cough

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Other changes 		BJIMAG 17,1,1960
inhalation
human 		lowest published toxic concentration: 1.02 mg/m3/6 hour N/R VCVPS* -,212,1998
inhalation
human 		lowest published toxic concentration: 1.02 mg/m3/6 hour Lung, Thorax, or Respiration: Respiratory depression VCVPS* -,212,1998
inhalation
mammal (species unspecified) 		lethal concentration : >16,250 mg/m3 N/R GTPZAB 35(4),38,1991
intraperitoneal
guinea pig 		lethal dose (50 percent kill): 4 gm/kg N/R JDGRAX 5(1),93,1973
intraperitoneal
rat 		lethal dose (50 percent kill): 2 gm/kg N/R JDGRAX 5(1),93,1973
oral
mouse 		lethal dose : >15 gm/kg N/R GTPZAB 35(4),38,1991
oral
rat 		lethal dose : >15 gm/kg N/R GTPZAB 35(4),38,1991


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lowest published toxic concentration: 21 mg/m3/6 hour/1 year- intermittent Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight 		TXAPA9 88,354,1987
inhalation
guinea pig 		lowest published toxic concentration: 580 µg/m3/6 hour/24 week- intermittent Lung, Thorax, or Respiration: Changes in lung weight

Blood: Changes in leukocyte (WBC) count

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases 		JEGPAY 54,171,1979


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.2 mg/m3 (G) DTLVS* TLV/BEI,2003
TOXICOLOGY REVIEW
JJOMDZ 14,199,1972


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 1 mg/m3 (dust) DTLVS* 3,60,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) see 1910.1043 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 1 mg/m3, raw dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 1 mg/m3, raw dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 1 ppm, raw dust CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - FINLAND time-weighted average 1 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.2 mg/m3, fiber, JAN1999
Occupational Exposure Limit - GERMANY MAK 1.5 mg/m3, JAN1999
Occupational Exposure Limit - INDIA time-weighted average 0.2 mg/m3, JAN1993
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1 mg/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.5 mg/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.32 mg/m3, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.2 mg/m3, 2003
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.5 mg/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.2 mg/m3 (G)
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.2 mg/m3 (G)


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COTTON DUST-air lowest feasible concentration NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969-
JEGPAY Journal of the Egyptian Public Health Association. (Egyptian Public Health Assoc., Shousha Bldg., Bloc. A, 31 Sharia 26 July, App. 116, Cairo, Egypt) V.1- 1926-
JJOMDZ JOM, Journal of Occupational Medicine. (American Occupational Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606) V.10- 1968-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVPS* "Vrednie chemichescie veshestva. Prirodnie organicheskie soedinenia" (Hazardous substances. Nature products.) Volkova N.V. et al., Sankt-Peterburg, 1998.

RTECS Compound Description:
   Human Data

ALT CAS #: N/R
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