The Registry of Toxic Effects of Chemical Substances

Cyclopropanecarboxylic acid, 2,2 - dimethyl - 3 - (2 - methyl - 1 - propenyl) - , 2 - methyl - 4 - oxo - 3 - (2 - propenyl) - 2 - cyclopenten - 1 - yl ester

RTECS #: GZ1925000

CAS #: 584-79-2

UPDATE: August 2003 MW: 302.45 MF: C19H26O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. (+) - Allelrethonyl (+) - cis,trans - chrysanthemate
  2. 3 - Allyl - 2 - methyl - 4 - oxo - 2 - cyclopenten - 1 - yl chrysanthemate
  3. 3 - Allyl - 4 - keto - 2 - methylcyclopentenyl chrysanthemummonocarboxylate
  4. Allethrin I
  5. Allethrin coil
  6. Allyl cinerin I
  7. Allylrethronyl dl - cis - trans - chrysanthemate
  8. Binamin forte
  9. Bioallethrin
  10. Bioaltrina (Portuguese)
  11. Chrysanthemummonocarboxylic acid, 3 - allyl - 2 - methyl - 4 - oxo - 2 - cyclopenten - 1 - yl ester (6CI)
  12. Depallethrin
  13. ENT 17,510
  14. Exthrin
  1. FDA 1446
  2. FMC 249
  3. NIA 249
  4. Necarboxylic acid
  5. OMS 468
  6. Pallethrine
  7. Pynamin - forte
  8. Pyresyn
  9. Wasp Stopper CF
  10. d,l - 2 - Allyl - 4 - hydroxy - 3 - methyl - 2 - cyclopenten - 1 - one - d,l - chrysanthemum monocarboxylate
  11. d - Allethrin
  12. d - trans Allethrin
  13. dl - 3 - Allyl - 2 - methyl - 4 - oxocyclopent - 2 - enyl dl - cis trans chrysanthemate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster lung 1,900 µg/L MUREAV 66,277,1979
mutation in microorganisms Salmonella typhimurium 500 µg/plate (-enzymatic activation step) MUREAV 116,185,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intracerebral
mouse 		lowest published lethal dose: 4 mg/kg N/R TXAPA9 66,290,1982
inhalation
mouse 		lethal concentration (50 percent kill): >2 gm/m3 N/R YKYUA6 37,187,1986
inhalation
rat 		lowest published lethal concentration: 13,800 mg/m3/4 hour Behavioral: Tremor

Behavioral: Excitement 		AMIHBC 2,420,1950
intraperitoneal
mouse 		lethal dose (50 percent kill): 38 mg/kg N/R JAFCAU 31,250,1983
intraperitoneal
rabbit 		lethal dose (50 percent kill): 11,200 mg/kg N/R WRPCA2 3,28,1964
intravenous
rat 		lowest published lethal dose: 4 mg/kg Behavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Aggression 		PCBPBS 2,308,1972
oral
mouse 		lethal dose (50 percent kill): 370 mg/kg N/R ABCHA6 28,914,1965
oral
quail 		lethal dose (50 percent kill): 2,030 mg/kg N/R PEMNDP 9,19,1991
oral
rat 		lethal dose (50 percent kill): 685 mg/kg N/R FMCHA2 -,C255,1991
oral
rabbit 		lethal dose (50 percent kill): 4,290 mg/kg N/R SPEADM 78-1,7,1978
skin
mouse 		lethal dose (50 percent kill): 1,200 mg/kg N/R ABCHA6 27,684,1963
skin
rat 		lethal dose (50 percent kill): 2,500 mg/kg N/R YKYUA6 37,187,1986
skin
rabbit 		lethal dose (50 percent kill): 11,332 mg/kg Behavioral: Tremor

Behavioral: Excitement 		AMIHBC 2,420,1950
unreported route
rat 		lethal dose (50 percent kill): 680 mg/kg N/R 30ZDA9 -,131,1971


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 21 gm/kg/12 week- intermittent Liver: Changes in liver weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Biochemical: Metabolism (intermediary): Other proteins 		BOCKAF 35,103,1970
unreported route
mouse 		lowest published toxic dose: 5.04 mg/kg/7 day- intermittent Brain and Coverings: Other degenerative changes HBPTO* 1,880,2001


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
JTCTDW 38,103,2000


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2264;
Number of Industries 2;
Total Number of Facilities 202;
Number of Occupations 2;
Total Number of Employees Exposed 1,366


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: In vitro UDS-human fibroblast; S cerevisiae-homozygosis
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42, 1937-77. Discontinued.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740)
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used as an insecticide

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

ALT CAS #: 137-98-4
ALT CAS #: 8018-12-0
ALT CAS #: 18877-88-8
ALT CAS #: 71119-51-2
ALT CAS #: 71211-88-6
 Click Here for Additional Information about RTECS