The Registry of Toxic Effects of Chemical Substances

Dichromic acid, diammonium salt

RTECS #: HX7650000

CAS #: 7789-09-5

UPDATE: May 2005 MW: 252.10 MF: Cr2H2O7•2H3N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Ammonio (bicromato di) (Italian)
  2. Ammonio (dicromato di) (Italian)
  3. Ammoniumbichromaat (Dutch)
  4. Ammonium bichromate
  5. Ammoniumdichromaat (Dutch)
  1. Ammoniumdichromat (German)
  2. Ammonium dichromate
  3. Ammonium dichromate (VI)
  4. Ammonium (dichromate d') (French)
  5. Bichromate d'ammonium (French)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Bacillus subtilis 50 mmol/L TOLED5 7,439,1981
DNA repair Salmonella typhimurium 50 mmol/L TOLED5 7,439,1981


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
child 		lowest published lethal dose: 99 mg/kg Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Change in clotting factors 		AEMED3 24,748,1994
subcutaneous
guinea pig 		lowest published lethal dose: 25 mg/kg N/R EQSSDX 1,1,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.05 mg(Cr)/m3 DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed human carcinogen DTLVS* TLV/BEI,1999
International Agency for Research on Cancer (IARC) Cancer Review Human Sufficient Evidence IMEMDT 49,49,1990
International Agency for Research on Cancer (IARC) Cancer Review Group 1 IMEMDT 49,49,1990
TOXICOLOGY REVIEW
85DHAX Cr,22,1974


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Cr)/m3 DTLVS* 3,35,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) ceiling concentration 0.1 mg(CrO3)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) ceiling concentration 0.1 mg(CrO3)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) ceiling concentration 0.1 mg(CrO3)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) ceiling concentration 0.1 mg(CrO3)/m3 CFRGBR 41,50-204.50,1994


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHROMIUM(VI)-air Carcinogen;
10 hour time-weighted average 0.001 mg(Cr)/m3 		NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 06063;
Number of Industries 31;
Total Number of Facilities 1,812;
Number of Occupations 15;
Total Number of Employees Exposed 13,389
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 06063;
Number of Industries 23;
Total Number of Facilities 3,088;
Number of Occupations 21;
Total Number of Employees Exposed 25,163;
Total Number of Female Employees Exposed 5,017


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in lithography and photoengraving, and in manufacture of special mordants and catalysts
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen


REFERENCES:

CODEN
REFERENCE
85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77
AEMED3 Annals of Emergency Medicine. (American College of Emergency Physicians, 1125 Executive Circle, Irving, TX 75038)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-

Used in lithography and photoengraving, and in manufacture of special mordants and catalysts

RTECS Compound Description:
   Tumorigen
   Mutagen
   Human Data

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