The Registry of Toxic Effects of Chemical Substances

Ethanamine

RTECS #: KH2100000

CAS #: 75-04-7

UPDATE: November 2004 MW: 45.10 MF: C2H7N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 1 - Aminoethane
  2. Aethylamine (German)
  3. Aminoethane
  4. Ethylamine
  1. Ethylamine (ACGIH:OSHA)
  2. Etilamina (Italian)
  3. Etyloamina (Polish)
  4. Monoethylamine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		5 mg severe UCDS** 4/25/1958
eye
rabbit 		50 ppm/10 day- intermittent severe AMIHBC 3,287,1951
eye
rabbit 		250 µg/24 hour severe 85JCAE -,429,1986
skin
rabbit 		500 mg/24 hour mild 85JCAE -,429,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mammal (species unspecified) 		lethal concentration (50 percent kill): 2,300 mg/m3 N/R TPKVAL 14,80,1975
inhalation
rat 		lethal concentration (50 percent kill): 5,540 ppm/1 hour Eye: Corneal damage

Lung, Thorax, or Respiration: Dyspnea 		NTIS** OTS0538173
intravenous
rabbit 		lowest published lethal dose: 350 mg/kg N/R HBAMAK 4,1295,1935
oral
rat 		lethal dose (50 percent kill): 400 mg/kg N/R AMIHBC 10,61,1954
skin
rabbit 		lethal dose (50 percent kill): 390 µL/kg N/R AMIHBC 10,61,1954


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm (skin) DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm (skin);short term exposure limit 15 ppm (skin) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 15 ppm (skin) DTLVS* TLV/BEI,2002
TOXICOLOGY REVIEW
CHREAY 9,389,1931


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 10 ppm (18 mg/m3) DTLVS* 3,103,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 10 ppm (18 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 10 ppm (18 mg/m3), Skin, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 10 ppm (18 mg/m3), short term exposure limit 20 ppm (37 mg/m3), Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 10 ppm (18 mg/m3), VLE 15 ppm (27 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 10 ppm (18 mg/m3), Skin, JAN1999
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 9 mg/m3, 2003
Occupational Exposure Limit - NORWAY time-weighted average 10 ppm (18 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 5 mg/m3, MAC(short term exposure limit) 15 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 10 ppm, JAN1993
Occupational Exposure Limit - SWEDEN NGV 10 ppm (18 mg/m3), KTV 15 ppm (30 mg/m3), Skin, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 10 ppm (18 mg/m3), KZG- week 20 ppm (36 mg/m3), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2 ppm (3.8 mg/m3, short term exposure limit 6 ppm (11 mg/m3), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 15 ppm (skin)
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 15 ppm (skin)


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHYLAMINE-air 10 hour time-weighted average 10 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 31520;
Number of Industries 9;
Total Number of Facilities 205;
Number of Occupations 11;
Total Number of Employees Exposed 4,982
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 31520;
Number of Industries 2;
Total Number of Facilities 31;
Number of Occupations 2;
Total Number of Employees Exposed 1,797;
Total Number of Female Employees Exposed 357


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #36


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.)
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

NIOSH PROFILE (AMINES, PRIMARY ALIPHATIC), SRI, 2/77

RTECS Compound Description:
   Primary Irritant

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