The Registry of Toxic Effects of Chemical Substances

Ethylene, chlorotrifluoro -

RTECS #: KV0525000

CAS #: 79-38-9


UPDATE: February 2004 MW: 116.47 MF: C2ClF3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Chlorotrifluoroethylene
  2. 1 - Chloro - 1,2,2 - trifluoroethylene
  3. 2 - Chloro - 1,1,2 - trifluoroethylene
  4. Chlortrifluoraethylen (German)
  5. CTFE
  6. Daiflon
  7. Ethene, chlorotrifluoro - (9CI)
  8. Ethylene, trifluorochloro -
  1. Genetron 1113
  2. Monochlorotrifluoroethylene
  3. Trifluorchlorethylen (Czech)
  4. Trifluorochloroethylene
  5. 1,1,2 - Trifluoro - 2 - chloroethylene
  6. Trifluoromonochloroethylene
  7. Trifluorovinyl chloride
  8. Trithene


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
guinea pig
lethal concentration (50 percent kill): 4,300 mg/m3/4 hour Behavioral: Somnolence (general depressed activity)

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
GTPZAB 21(5),36,1977
inhalation
mouse
lethal concentration (50 percent kill): 3,000 ppm/7 hour N/R ABMGAJ 21,377,1968
inhalation
mouse
lethal concentration (50 percent kill): 4,740 mg/m3/24 hour N/R VCVGH* -,661,1990
inhalation
mouse
lethal concentration (50 percent kill): 13,200 mg/m3/7 hour N/R VCVGH* -,661,1990
inhalation
mouse
lethal concentration (50 percent kill): 37,900 mg/m3/3 hour N/R VCVGH* -,661,1990
inhalation
rat
lethal concentration (50 percent kill): 1,000 ppm/4 hour Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Other changes
FLCRAP 1,197,1967
inhalation
rat
lethal concentration (50 percent kill): 7,100 mg/m3/4 hour N/R VCVGH* -,661,1990
inhalation
rabbit
lethal concentration (50 percent kill): 27,000 mg/m3/2 hour N/R VCVGH* -,661,1990
intraperitoneal
mouse
lethal dose (50 percent kill): 175 mg/kg N/R ABMGAJ 21,377,1968
oral
mouse
lethal dose (50 percent kill): 268 mg/kg N/R ABMGAJ 21,377,1968


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
guinea pig
lowest published toxic concentration: 300 ppm/4 hour/4 week- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTIS** OTS0571342
inhalation
rabbit
lowest published toxic concentration: 300 ppm/4 hour/4 week- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field NTIS** OTS0571342


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84524;
Number of Industries 4;
Total Number of Facilities 66;
Number of Occupations 7;
Total Number of Employees Exposed 1,429


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as polymer precursor
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT.
FLCRAP Fluorine Chemistry Reviews. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1967-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Used as polymer precursor

RTECS Compound Description:
   Drug

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