The Registry of Toxic Effects of Chemical Substances

Hydrobromic acid

RTECS #: MW3850000

CAS #: 10035-10-6

UPDATE: May 2004 MW: 80.92 MF: BrH


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Acide bromhydrique (French)
  2. Acido bromidrico (Italian)
  3. Anhydrous hydrobromic acid
  4. Bromowodor (Polish)
  1. Bromwasserstoff (German)
  2. Broomwaterstof (Dutch)
  3. Hydrogen bromide
  4. Hydrogen bromide (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lethal concentration (50 percent kill): 814 ppm/1 hour N/R NTIS** PB214-270
inhalation
rat 		lethal concentration (50 percent kill): 2,858 ppm/1 hour N/R NTIS** PB214-270
inhalation
rat 		lowest published toxic concentration: 26 mg/m3 Olfaction: Change in sensation of smell

Lung, Thorax, or Respiration: Dyspnea 		VCVN5* -,393,1989
intraperitoneal
rat 		lethal dose (50 percent kill): 76 mg/kg N/R GISAAA 41(1),105,1976


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 3 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 3 ppm (10 mg/m3) DTLVS* 3,128,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 3 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 3 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM short term exposure limit 3 ppm (9.9 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 3 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND short term exposure limit 3 ppm (10 mg/m3), Skin, JAN1999
Occupational Exposure Limit - GERMANY MAK 5 ppm (17 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 3 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 3 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 7 mg/m3, MAC(short term exposure limit) 21 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 2 mg/m3, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 3 ppm (10 mg/m3), KZG- week 6 ppm (20 mg/m3), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 5 ppm (17 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM short term exposure limit 3 ppm (10 mg/m3), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

ceiling concentration 3 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 3 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN BROMIDE-air ceiling concentration 3 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 38575;
Number of Industries 13;
Total Number of Facilities 510;
Number of Occupations 12;
Total Number of Employees Exposed 2,643
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 38575;
Number of Industries 23;
Total Number of Facilities 1,103;
Number of Occupations 26;
Total Number of Employees Exposed 20,571;
Total Number of Female Employees Exposed 5,398


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in the manufacture of intermediates for pharmaceuticals, dyes, photographic chemicals
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Acids, inorganic, 7903


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

Used in the manufacture of intermediates for pharmaceuticals, dyes, photographic chemicals

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