The Registry of Toxic Effects of Chemical Substances

Hydrogen peroxide, 90%

RTECS #: MX0900000

CAS #: 7722-84-1


UPDATE: February 2005 MW: 34.02 MF: H2O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. Albone
  2. Dihydrogen dioxide
  3. Hioxyl
  4. Hydrogen dioxide
  5. Hydrogen peroxide
  6. Hydrogen peroxide (ACGIH:OSHA)
  7. Hydroperoxide
  8. Inhibine
  9. Oxydol
  10. Perhydrol
  1. Perone
  2. Perossido di idrogeno (Italian)
  3. Peroxan
  4. Peroxide
  5. Peroxyde d'hydrogene (French)
  6. Superoxol
  7. T - Stuff
  8. Wasserstoffperoxid (German)
  9. Waterstofperoxyde (Dutch)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
1 mg severe JTPAE7 29,308,2001


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis hamster ovary 1 mmol/L CALEDQ 5,199,1978
cytogenetic analysis hamster lung 100 µmol/L IDZAAW 56,1,1981
cytogenetic analysis hamster embryo 100 µmol/L IDZAAW 56,1,1981
cytogenetic analysis hamster fibroblast 250 mg/L ESKHA5 (96),55,1978
cytogenetic analysis mouse Ascites tumor 10 mmol/L MUREAV 4,385,1967
cytogenetic analysis mouse embryo 10 µmol/L IDZAAW 56,1,1981
DNA adduct hamster embryo 0.9 µmol/L/1 hour MUREAV 563,35,2004
DNA damage Bacillus subtilis 50 mmol/L BBACAQ 155,476,1968
DNA damage cattle other cell types 25 µmol/L MUREAV 240,35,1990
DNA damage Escherichia coli 0.1 µmol/plate/2 hour MUREAV 535,171,2003
DNA damage hamster ovary 20 µmol/L MUREAV 299,95,1993
DNA damage hamster lung 353 µmol/L NATUAS 282,318,1979
DNA damage hamster lung 100 mmol/L/1 hour MUTAEX 17,45,2002
DNA damage hamster lung 200 µmol/L/24 hour ARTODN 75,604,2001
DNA damage hamster ovary 200 µmol/L/5 minute MUREAV 560,41,2004
DNA damage human fibroblast 28 µmol/L BBACAQ 781,56,1984
DNA damage human other cell types 100 µmol/L CNREA8 45,2522,1985
DNA damage human lymphocyte 100 µmol/L JCINAO 77,1312,1986
DNA damage human leukocyte 20 µmol/L MUREAV 265,255,1992
DNA damage human lung 300 µmol/L/1 hour MUREAV 515,99,2002
DNA damage human other cell types 100 µmol/L/3 hour MUTAEX 16,439,2001
DNA damage human other cell types 10 µmol/L/15 minute MUREAV 519,151,2002
DNA damage human lymphocyte 0.1 mmol/L/5 minute MUREAV 508,157,2002
DNA damage human lymphocyte 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage human other cell types 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage human other cell types 0.375 mmol/L/5 minute MUREAV 526,19,2003
DNA damage human lymphocyte 0.1 mmol/L/30 minute TCMUD8 20,11,2000
DNA damage human other cell types 10 mmol/L/10 minute MUREAV 537,1,2003
DNA damage human sperm 80 µmol/L/1 hour MUREAV 544,173,2003
DNA damage human lymphocyte 1 µmol/L/2 hour TOSCF2 72,283,2003
DNA damage mammal (species unspecified) lymphocyte 600 µmol/L DECRDP 8,1,1982
DNA damage mouse other cell types 100 µmol/L JCINAO 77,1312,1986
DNA damage mouse other cell types 1 µmol/L CRNGDP 4,1507,1983
DNA damage mouse lymphocyte 2 mmol/L MUREAV 203,155,1988
DNA damage mouse other cell types 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage mouse other cell types 200 µmol/L/1 hour (-enzymatic activation step) MUREAV 541,9,2003
DNA damage mouse fibroblast 25 µmol/L/15 minute MUREAV 531,165,2003
DNA damage non-mammalian species other cell types 0.4 mmol/L/1 hour MUREAV 539,19,2003
DNA damage non-mammalian species other cell types 44 µmol/L/20 minute MUREAV 542,15,2003
DNA damage Neurospora crassa 50 µmol/L MUREAV 405,29,1998
DNA damage other fish other cell types 0.1 mmol/L/5 minute MUREAV 534,165,2003
DNA damage other microorganisms 1 mmol/L MUREAV 368,235,1996
DNA damage rat other cell types 200 µmol/L CRNGDP 20,629,1999
DNA damage rat liver 300 µmol/L/1 hour MUREAV 515,99,2002
DNA damage rat other cell types 10 µmol/L/24 hour ATSUDG 75,243,2001
DNA damage salmon embryo 5 µmol/L/1 hour MUREAV 563,89,2004
DNA inhibition human other cell types 1,200 µmol/L CNREA8 45,2522,1985
DNA inhibition human fibroblast 1 mg/L CRNGDP 4,1317,1983
DNA inhibition mouse other cell types 40 µmol/L JCINAO 77,1312,1986
DNA repair Escherichia coli 14,630 µg/well/16 hour CBINA8 15,219,1976
DNA repair human fibroblast 20 µmol/L/1 hour MUREAV 513,159,2002
DNA repair human other cell types 10 mmol/L/10 minute MUREAV 537,1,2003
DNA repair Salmonella typhimurium 2 mmol/L/60 minute MUREAV 502,11,2002
unscheduled DNA synthesis human fibroblast 1 mmol/L CALEDQ 5,199,1978
unscheduled DNA synthesis human lung 600 µg/L ENMUDM 5,177,1983
mutation in microorganisms Bacillus subtilis 5 ppm (-enzymatic activation step) MUREAV 95,191,1982
mutation in microorganisms Bacillus subtilis 5 pph/15 minute MUREAV 503,77,2002
mutation in microorganisms Escherichia coli 5 pph (-enzymatic activation step) AGACBH 4,286,1974
mutation in microorganisms Escherichia coli 100 µg/plate/48 hour (+/-enzymatic activation step) MUREAV 539,29,2003
mutation in microorganisms Haemophilus influenzae 800 µmol/L (-enzymatic activation step) MUREAV 30,9,1975
mutation in microorganisms Neurospora crassa 210 mmol/L/30 minute (-enzymatic activation step) PNASA6 35,581,1949
mutation in microorganisms other microorganisms 6 ppm/1 hour- continuous (-enzymatic activation step) JOBAAY 54,767,1947
mutation in microorganisms other microorganisms 6 ppm (-enzymatic activation step) POASAD 34,114,1953
mutation in microorganisms Salmonella typhimurium 6 µg/plate (-enzymatic activation step) ABCHA6 44,1989,1980
mutation in microorganisms Salmonella typhimurium 200 µg/plate/72 hour (-enzymatic activation step) TOLED5 116,189,2000
mutation in microorganisms Salmonella typhimurium 1.87 mg/plate/30 minute MUREAV 535,171,2003
mutation in microorganisms Salmonella typhimurium 25 µg/plate/48 hour (+/-enzymatic activation step) MUREAV 539,29,2003
mutation in microorganisms Salmonella typhimurium 500 µg/plate/66 hour (-enzymatic activation step) EMMUEG 40,63,2002
mutation in microorganisms Salmonella typhimurium 34,000 ng/plate/72 hour MUREAV 542,49,2003
mutation in microorganisms Saccharomyes cerevisiae 10 mg/L (-enzymatic activation step) MUREAV 33,147,1975
mutation in microorganisms Schizosaccharomyces pombe 2,820 mmol/L (-enzymatic activation step) ADWMAX -,193,1962
micronucleus test hamster embryo 5 mg/L/4 hour (-enzymatic activation step) MUREAV 561,153,2004
gene conversion and mitotic recombination Saccharomyes cerevisiae 5 pph AGACBH 4,286,1974
mutation in mammalian somatic cells hamster lung 10 µmol/L CRNGDP 10,1055,1989
mutation in mammalian somatic cells monkey kidney 7 mmol/L CRNGDP 11,283,1990
mutation in mammalian somatic cells mouse lymphocyte 18,600 nmol/L MUTAEX 3,193,1988
morphological transform hamster embryo 2,500 µg/L MUREAV 356,85,1996
morphological transform mouse embryo 20 µmol/L CRNGDP 10,1055,1989
morphological transform rat liver 100 µmol/L/7 week MOCAE8 30,209,2001
other mutation test systems Bacillus subtilis 100 µmol/L MUREAV 4,517,1967
other mutation test systems Escherichia coli 100 µmol/L MUREAV 203,81,1988
other mutation test systems human other cell types 1,200 µmol/L CNREA8 45,2522,1985
other mutation test systems Salmonella typhimurium 45 mg/L MUREAV 192,239,1987
phage inhibition capacity Escherichia coli 500 ng/well MUREAV 260,349,1991
sister chromatid exchange hamster lung 40 µmol/L MUREAV 174,21,1986
sister chromatid exchange hamster ovary 80 µmol/L MUREAV 224,269,1989
specific locus test Escherichia coli 2.5 mmol/L/10 minute MUREAV 508,107,2002
specific locus test Escherichia coli 1 µmol/L/4 hour MUREAV 560,27,2004
specific locus test mouse kidney 65 µmol/L MUREAV 503,69,2002


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lowest published toxic dose: 144 gm/kg/26 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Tumors
GANNA2 75,17,1984
oral
mouse
toxic dose : 168 gm/kg/30 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Tumors
GANNA2 75,17,1984


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 10 mg/m3 Skin: After topical application: Primary irritation VCVN1* -,18,1998
inhalation
human
lowest published toxic concentration: 20 mg/m3 Peripheral Nerve and Sensation: Flaccid paralysis with appropriate anesthesia

Behavioral: Tetany

Cardiac: Arrythmias (indlucing changes in conduction)
VCVN1* -,18,1998
inhalation
mammal (species unspecified)
lowest published toxic concentration: 60 mg/m3/4 hour Skin: After topical application: Primary irritation VCVN1* -,17,1998
inhalation
mouse
lowest published lethal concentration: 227 ppm N/R AEHLAU 4,327,1962
inhalation
rat
lethal concentration (50 percent kill): 2 gm/m3/4 hour Lung, Thorax, or Respiration: Pulmonary emboli GTPZAB 21(10),22,1977
inhalation
rat
lethal concentration (50 percent kill): 2,000 mg/m3 N/R VCVN1* -,17,1998
intraperitoneal
mouse
lethal dose (50 percent kill): 880 mg/kg N/R VCVN1* -,17,1998
intravenous
dog
lowest published toxic dose: 0.3 mg/kg Behavioral: Excitement

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
intravenous
horse, donkey
lowest published toxic dose: 40 µg/kg Cardiac: Pulse rate increased without fall in BP

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Hypermotility, diarrhea
VCVN1* -,17,1998
intravenous
rabbit
lethal dose (50 percent kill): 15 gm/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
intravenous
rabbit
lowest published lethal dose: 0.4 mg/kg Behavioral: Tremor

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
oral
mouse
lethal dose (50 percent kill): 2,000 mg/kg N/R VCVN1* -,17,1998
oral
rat
lethal dose (50 percent kill): 376 mg/kg Gastrointestinal: Peritonitis

Blood: Pigmented or nucleated red blood cells

Blood: Changes in leukocyte (WBC) count
STGNBT -,39,1999
oral
rat
lethal dose (50 percent kill): 4,050 mg/kg N/R VCVN1* -,17,1998
subcutaneous
mouse
lethal dose (50 percent kill): 1,072 mg/kg N/R GISAAA 48(6),28,1983
subcutaneous
rat
lethal dose (50 percent kill): 620 mg/kg N/R VCVN1* -,17,1998
skin
mammal (species unspecified)
lowest published toxic concentration: 110 mg/m3 Cardiac: Pulse rate increased without fall in BP

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
skin
mouse
lethal dose (50 percent kill): 1,072 mg/kg N/R VCVN1* -,17,1998
skin
mouse
lowest published toxic concentration: 10 pph Vascular: Other changes VCVN1* -,18,1998
skin
pig
lowest published lethal dose: 2 gm/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
skin
rat
lethal dose (50 percent kill): 4,060 mg/kg Lung, Thorax, or Respiration: Pulmonary emboli GTPZAB 21(10),22,1977
skin
rat
lethal concentration (50 percent kill): 4,060 mg/m3 Lung, Thorax, or Respiration: Other changes

Biochemical: Effect on specific coenzyme: Disturbed regulation
VCVN1* -,17,1998
skin
rabbit
lowest published lethal dose: 500 mg/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
skin
rabbit
lowest published lethal concentration: 15 pph Eye: Lacrimation

Behavioral: Headache

Lung, Thorax, or Respiration: Cough
VCVN1* -,18,1998


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lowest published toxic concentration: 7 ppm/6 hour/26 week- intermittent Skin: After systemic exposure: Dermatitis, other

Skin and Appendages: Other: Hair
AMIHBC 10,319,1954
inhalation
mouse
lowest published toxic concentration: 57 ppm/6 hour/6 week- intermittent Skin: After systemic exposure: Dermatitis, irritative

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AMIHBC 10,319,1954
inhalation
rat
lowest published toxic concentration: 67 ppm/6 hour/6 week- intermittent Skin: After systemic exposure: Dermatitis, irritative

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AMIHBC 10,319,1954
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/17 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Monoamine oxidase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
GTPZAB 21(10),22,1977
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/8 week- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases VCVN1* -,18,1998
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/17 week- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
VCVN1* -,18,1998
oral
rat
lowest published toxic dose: 8.75 mg/kg/25 week- continuous Endocrine: Effect on menstrual cycle

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN1* -,19,1988
oral
rabbit
lowest published toxic dose: 8.75 mg/kg/25 week- continuous Endocrine: Effect on menstrual cycle

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN1* -,19,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed Animal Carcinogen with Unknown DTLVS* TLV/BEI,2003
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 36,285,1985
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 71,671,1999
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 36,285,1985
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 71,671,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 71,671,1999
TOXICOLOGY REVIEW
MUREAV 566,99,2004
TOXICOLOGY REVIEW
MUREAV 544,179,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: RED Completed RBREV* -,330,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 1 ppm (1.4 mg/m3) DTLVS* 3,131,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 1 ppm (1.5 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 1 ppm (1.4 mg/m3), JAN1993
Occupational Exposure Limit - FINLAND time-weighted average 1 ppm (1.4 mg/m3), short term exposure limit 3 ppm (4.2 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 1 ppm (1.5 mg/m3), JAN1993
Occupational Exposure Limit - GERMANY MAK 1 ppm (1.4 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 1 ppm (1.4 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1 ppm (1.4 mg/m3), JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1.4 mg/m3, 2003
Occupational Exposure Limit - TURKEY time-weighted average 1 ppm (1.4 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1 ppm (1.4 mg/m3, short term exposure limit 2 ppm (2.8 mg/m3), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed Animal Carcinogen with Unknown
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed Animal Carcinogen with Unknown


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN PEROXIDE-air 10 hour time-weighted average 1.0 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 38605;
Number of Industries 168;
Total Number of Facilities 19,597;
Number of Occupations 83;
Total Number of Employees Exposed 422,227
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 38605;
Number of Industries 171;
Total Number of Facilities 22,930;
Number of Occupations 142;
Total Number of Employees Exposed 1,006,752;
Total Number of Female Employees Exposed 727,702


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an industrial chemical, food and feed additive, flavor, packaging material
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8799
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
ADWMAX Abhandlungen der Deutschen Akademie der Wissenschaften zu Berlin, Klasse fuer Medizin. (Berlin, Ger. Dem. Rep.) 1950-68. Discontinued.
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960-
AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70-
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947-
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG.
ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP.
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924-
JOBAAY Journal of Bacteriology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1916-
JTPAE7 Journal of Toxicologic Pathology. (Nihon Dokusei Byori Gakkai, editor, 3-25-8 Nishi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988
MOCAE8 Molecular Carcinogenesis. (John Wiley & Sons, 605 Third Avenue, New York, NY 10158) V.1- 1988-
MRLR** U.S. Army, Chemical Corps Medical Laboratories Research Reports. (Army Chemical Center, Edgewood Arsenal, MD)
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915-
POASAD Proceedings of the Oklahoma Academy of Science. (Oklahoma Academy of Science, c/o Executive Secretary-Treasurer, Southwestern Oklahoma State Univ., Weatherford, OK 73096) V.1- 1910/1920-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TOSCF2 Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as an industrial chemical, food and feed additive, flavor, packaging material

NIOSH PROFILE (HAIRDRESSING and BARBERS), SRC, 6/80

NIOSH PROFILE (PHOTOGRAPHIC PROCESSING), FIRL, 4/78

FDA-over the counter drug

RTECS Compound Description:
   Tumorigen
   Drug
   Mutagen
   Human Data
   Hormone
   Primary Irritant

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