The Registry of Toxic Effects of Chemical Substances

Indene

RTECS #: NK8225000

CAS #: 95-13-6

UPDATE: November 2004 MW: 116.17 MF: C9H8


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Inden
  2. Indonaphthene
  1. Indene (ACGIH:OSHA)
  2. 1H - Indene


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 14 gm/m3 N/R GISAAA 41(4),104,1976
inhalation
rat 		lethal concentration (50 percent kill): 14,000 mg/m3/4 hour N/R VCVGH* -,218,1990
oral
mammal (species unspecified) 		lethal dose (50 percent kill): >5 gm/kg N/R GISAAA 39(4),86,1974
unreported route
mouse 		lethal dose (50 percent kill): 1,800 mg/kg N/R VCVGH* -,218,1990
unreported route
rat 		lethal dose (50 percent kill): 2,300 mg/kg N/R VCVGH* -,218,1990


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 3 mg/m3/24 hour/15 week- continuous Kidney, Ureter, and Bladder: Other changes in urine composition

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases 		GISAAA 41(4),104,1976


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 10 ppm (45 mg/m3) DTLVS* 3,134,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 10 ppm (45 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 10 ppm (45 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 ppm (45 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 10 ppm (48 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 10 oom (45 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 10 ppm (47 mg/m3), short term exposure limit 20 ppm (95 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 10 ppm (45 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 10 ppm (45 mg/m3), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 10 ppm (45 mg/m3), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 45 mg/m3, 2003
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO INDENE-air 10 hour time-weighted average 10 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 39820;
Number of Industries 24;
Total Number of Facilities 3,158;
Number of Occupations 42;
Total Number of Employees Exposed 61,824
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 39820;
Number of Industries 1;
Total Number of Facilities 31;
Number of Occupations 1;
Total Number of Employees Exposed 753;
Total Number of Female Employees Exposed 376


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

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