The Registry of Toxic Effects of Chemical Substances

Lithium hydroxide

RTECS #: OJ6307070

CAS #: 1310-65-2

UPDATE: December 2000 MW: 23.95 MF: HLiO


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Lithium hydroxide (Li (OH) ) (9CI)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 960 mg/m3/4 hour Lung, Thorax, or Respiration: Other changes FAATDF 7,58,1986
intratracheal
rat 		lethal dose (50 percent kill): 8,200 µg/kg Lung, Thorax, or Respiration: Other changes

Blood: Hemorrhage 		STGNBT -,152,1999
oral
mouse 		lethal dose (50 percent kill): 363 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		STGNBT -,152,1999
oral
rat 		lethal dose (50 percent kill): 210 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		STGNBT -,152,1999
subcutaneous
mouse 		lowest published lethal dose: 300 mg/kg N/R PHTXA6 21,419,1958


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mammal (species unspecified) 		lowest published toxic concentration: 8 mg/m3/4 hour/30 day- intermittent Lung, Thorax, or Respiration: Other changes STGNBT -,152,1999
oral
mammal (species unspecified) 		lowest published toxic dose: 9,100 µg/kg/26 week- intermittent Liver: Liver function tests impaired

Blood: Pigmented or nucleated red blood cells

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		STGNBT -,152,1999


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 1 mg/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM short term exposure limit 1 mg/m3, SEP2000


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 81879;
Number of Industries 157;
Total Number of Facilities 12,157;
Number of Occupations 79;
Total Number of Employees Exposed 145,575
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 81879;
Number of Industries 126;
Total Number of Facilities 14,044;
Number of Occupations 73;
Total Number of Employees Exposed 170,966;
Total Number of Female Employees Exposed 14,882


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in LITHIUM greases manufacturing, CO2 absorption, catalyst, and heat sink material
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Alkaline dusts, 7401


REFERENCES:

CODEN
REFERENCE
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued.
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999

Used in LITHIUM greases manufacturing, CO2 absorption, catalyst, and heat sink material

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