The Registry of Toxic Effects of Chemical Substances
Molybdenum |
UPDATE: May 2004 | MW: 95.94 | MF: Mo |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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cytogenetic analysis
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inhalation | rat
19,500 µg/m3
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GTPZAB 24(9),33,1980
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | mouse
lowest published toxic dose: 448 mg/kg (multigenerations)
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Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) | Reproductive: Effects on embryo or fetus: Fetal death
AEHLAU 23,102,1971
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oral | rat
lowest published toxic dose: 6,050 µg/kg (35 week prior to copulation)
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Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea) | Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) Reproductive: Specific developmental abnormalities: Musculoskeletal system
GISAAA 42(8),30,1977
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oral | rat
lowest published toxic dose: 5,800 µg/kg (30 week prior to copulation/1-20 day pregnant)
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Reproductive: Specific developmental abnormalities: Musculoskeletal system
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FATOAO 41,620,1978
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intratracheal | rabbit
lowest published lethal dose: 70 mg/kg
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Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)
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NTIS** PB249-458
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | rat
lowest published toxic dose: 7 mg/kg/2 week- intermittent
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Liver: Other changes | Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
VCVN5* -,317,1989
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oral | rabbit
lowest published toxic dose: 66.5 mg/kg/19 week- intermittent
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Liver: Other changes | Kidney, Ureter, and Bladder: Other changes Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN5* -,317,1989
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average 0.5 mg/m3 (R)
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DTLVS* TLV/BEI,2003
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Confirmed Animal Carcinogen with Unknown
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DTLVS* TLV/BEI,2003
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TOXICOLOGY REVIEW
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JAVMA4 164,277,1974
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TOXICOLOGY REVIEW
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FOREAE 7,313,1942
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TOXICOLOGY REVIEW
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KOTTAM 11,1300,1975
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 48625; | Number of Industries 17; Total Number of Facilities 935; Number of Occupations 29; Total Number of Employees Exposed 6,097
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X5919 | ![]() Number of Industries 2; Total Number of Facilities 29; Number of Occupations 6; Total Number of Employees Exposed 2,426; Total Number of Female Employees Exposed 1,114
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X5984 | ![]() Number of Industries 5; Total Number of Facilities 187; Number of Occupations 11; Total Number of Employees Exposed 4,474; Total Number of Female Employees Exposed 2,432
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 48625 |
![]() Number of Industries 173; Total Number of Facilities 15,780; Number of Occupations 88; Total Number of Employees Exposed 238,124; Total Number of Female Employees Exposed 4,166 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as alloying element
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EPA TSCA Section 8(d) unpublished health/safety studies
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On EPA IRIS database
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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NIOSH Analytical Method, 1994: Elements by ICP, 7300
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NIOSH Analytical Method, 1994: Metals in urine, 8310
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NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
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OSHA ANALYTICAL METHOD #ID121
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OSHA ANALYTICAL METHOD #ID125G
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REFERENCES:
CODEN
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REFERENCE
AEHLAU
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Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC
20016) V.1- 1960-
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DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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FATOAO
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Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939-
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FOREAE
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Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ.
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GISAAA
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Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936-
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GTPZAB
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Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
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JAVMA4
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Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc.,
930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915-
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KOTTAM
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Kogai to Taisaku. Journal of Environmental Pollution Control. (Kogai Taisaku Gijutsu
Dokokai, Shuwa-Akasaka Bldg., 9-1-244, Akasaka, Minato-ku, Tokyo 107, Japan) V.1- 1965-
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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VCVN5*
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"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous
substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al.,
Chimia, 1989.
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