The Registry of Toxic Effects of Chemical Substances
Palygorskite RTECS #: RT6400000
CAS #: 12174-11-7
The Registry of Toxic Effects of Chemical Substances
Palygorskite |
| UPDATE: October 1997 | MW: N/R | MF: N/R |
SYNONYMS:
|
|
| |
SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lowest published toxic concentration: 10 mg/m3/6 hour/13 week- intermittent
|
Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Lung, Thorax, or Respiration: Tumors
BJIMAG 44,749,1987
|
implant | rat
lowest published toxic dose: 200 mg/kg
|
Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Tumorigenic: Tumors at site of application
JJIND8 67,965,1981
|
intraperitoneal | rat
lowest published toxic dose: 338 mg/kg/2 week- intermittent
|
Tumorigenic: Neoplastic by RTECS criteria | Tumorigenic: Tumors at site of application
ZHPMAT 162,467,1976
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review
|
Animal Limited Evidence
|
IMEMDT 42,159,1987
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Animal Sufficient (>5um)
|
IMEMDT 68,245,1997
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Human Inadequate Evidence
|
IMEMDT 42,159,1987
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Human Inadequate Evidence
|
IMEMDT 68,245,1997
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Animal Inadequate (<5um)
|
IMEMDT 68,245,1997
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Group 2B (fibre >5um)
|
IMEMDT 68,245,1997
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Group 3 (fibre >5um)
|
IMEMDT 68,245,1997
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: X2204 |
 ;Number of Industries 8; Total Number of Facilities 576; Number of Occupations 9; Total Number of Employees Exposed 8,199 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA Section 8(d) unpublished health/safety studies
|
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
|
| |||
REFERENCES:
CODEN
|
|
REFERENCE
BJIMAG
|
British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME
04046) V.1- 1944-
|
IMEMDT
|
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
|
JJIND8
|
JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For
publisher information, see JNCIEQ.
|
ZHPMAT
|
Zentralblatt fuer Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abteilung
1: Originale, Reihe B: Hygiene, Krankenhaushygiene, Betriebshygiene, Praeventive Medizin.
(Stuttgart, Fed. Rep. Ger.) V.155-169, 1971-1979. For publisher information, see ZAOMDC.
|
| |