The Registry of Toxic Effects of Chemical Substances

2 - Pentanol, 4 - methyl - , acetate

RTECS #: SA7525000

CAS #: 108-84-9

UPDATE: November 2004 MW: 144.24 MF: C8H16O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 1,3 - Dimethylbutyl acetate
  2. 1,3 - Dimethylbutylester kyseliny octove (Czech)
  3. 4 - Methyl - 2 - pentanol, acetate
  4. 4 - Methyl - 2 - pentyl acetate
  5. Acetic acid, 1,3 - dimethylbutyl ester
  6. MAAC
  1. Methylisoamyl acetate
  2. Methylisobutylcarbinol acetate
  3. Methylisobutylcarbinyl acetate
  4. sec - Hexyl acetate
  5. sec - Hexyl acetate (ACGIH:OSHA)
  6. sek.Isohexylester kyseliny octove (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
human 		100 ppm/15 minute N/R JIHTAB 28,262,1946
skin
rabbit 		500 mg open irritation test mild UCDS** 7/28/1966


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
human 		lowest published toxic concentration: 100 ppm Olfaction: Other olfaction effects

Eye: Conjunctiva irritation

Lung, Thorax, or Respiration: Other changes 		JIHTAB 28,262,1946
inhalation
rat 		lowest published lethal concentration: 2,000 ppm/4 hour N/R UCDS** 7/28/1966
oral
rat 		lethal dose (50 percent kill): 6,160 mg/kg N/R UCDS** 7/28/1966
skin
rabbit 		lethal dose (50 percent kill): >20 mL/kg N/R AMIHBC 10,61,1954


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 50 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 50 ppm (300 mg/m3) DTLVS* 3,127,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 50 ppm (300 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 50 ppm (300 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 50 ppm (300 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 50 ppm (300 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 50 ppm (300 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 50 ppm (300 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 50 ppm (295 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 50 ppm (300 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 50 ppm (300 mg/m3), short term exposure limit 75 ppm (450 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 50 ppm (300 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 50 ppm (300 mg/m3), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 300 mg/m3, 2003
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 50 ppm (300 mg/m3), JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (300 mg/m3), KZG- week 100 ppm (600 mg/m3),JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 50 ppm (300 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 50 ppm (299 mg/m3), short term exposure limit 100 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 50 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 50 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO sec-HEXYL ACETATE-air 10 hour time-weighted average 50 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: T1668;
Number of Industries 1;
Total Number of Facilities 5;
Number of Occupations 1;
Total Number of Employees Exposed 20
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: T1668;
Number of Industries 1;
Total Number of Facilities 15;
Number of Occupations 1;
Total Number of Employees Exposed 145


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Esters I, 1450


REFERENCES:

CODEN
REFERENCE
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

RTECS Compound Description:
   Human Data
   Primary Irritant

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