The Registry of Toxic Effects of Chemical Substances

Perchloric acid, sodium salt

RTECS #: SC9800000

CAS #: 7601-89-0

UPDATE: January 1997 MW: 122.44 MF: ClO4•Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Natriumperchloraat (Dutch)
  2. Natriumperchlorat (German)
  3. Perchlorate de sodium (French)
  1. Sodio (perclorato di) (Italian)
  2. Sodium (perchlorate de) (French)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Escherichia coli 1,500 pmol/plate MUREAV 21,171,1973


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 551 mg/kg N/R COREAF 257,791,1963
oral
rat 		lethal dose (50 percent kill): 2,100 mg/kg Behavioral: Excitement

Lung, Thorax, or Respiration: Dyspnea

Nutritional and Gross Metabolic: Body temperature decrease 		GTPZAB 17(8),33,1973
parenteral
rat 		lowest published lethal dose: 900 mg/kg N/R RPTOAN 32,159,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 22,500 mg/kg/45 day- intermittent Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Biochemical: Metabolism (intermediary): Effect on mitochondrial function 		JEBIDP 13,149,1992


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1183;
Number of Industries 2;
Total Number of Facilities 57;
Number of Occupations 2;
Total Number of Employees Exposed 255
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1183;
Number of Industries 2;
Total Number of Facilities 14;
Number of Occupations 2;
Total Number of Employees Exposed 1,452;
Total Number of Female Employees Exposed 230


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JEBIDP Journal of Environmental Biology. (Academy of Environmental Biology, India, 657/5, Civil Lines (South), Muzaffarnagar, 251001, India) V.1- 1980-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967-

Used in analytical chemistry pyrotechnics

RTECS Compound Description:
   Mutagen

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