The Registry of Toxic Effects of Chemical Substances

Perchloryl fluoride

RTECS #: SD1925000

CAS #: 7616-94-6

UPDATE: November 2004 MW: 102.45 MF: ClFO3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Chlorine fluoride oxide
  2. Chlorine oxyfluoride
  1. Perchloryl fluoride (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
dog 		lowest published lethal concentration: 451 ppm/4 hour Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis

Gastrointestinal: Nausea or vomiting 		XAWPA2 CWL 2-10,1958
inhalation
guinea pig 		lethal concentration (50 percent kill): 220 mg/m3 Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)

Blood: Methemoglobinemia- Carboxhemoglobinemia

Blood: Changes in erythrocyte (RBC) count 		STGNBT -,199,1999
inhalation
mouse 		lethal concentration (50 percent kill): 630 ppm/4 hour N/R PENNS*
inhalation
rat 		lethal concentration (50 percent kill): 385 ppm/4 hour N/R PENNS*


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 3 ppm DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 3 ppm;short term exposure limit 6 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 6 ppm DTLVS* TLV/BEI,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 3 ppm (14 mg/m3) DTLVS* 3,202,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 3 ppm (13.5 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 3 ppm (13.5 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 3 ppm (13.5 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 3 ppm (13.5 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 3 ppm (14 mg/m3), short term exposure limit 6 ppm, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 2.5 mg(F)/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 3 ppm (13 mg/m3), short term exposure limit 6 ppm (25 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 3 ppm (14 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 3 ppm (14 mg/m3), short term exposure limit 6 ppm (25 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 3 ppm (14 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 3 ppm (14 mg/m3), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 14 mg/m3, 2003
Occupational Exposure Limit - SWEDEN NGV 2 mg(F)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 3 ppm (13 mg/m3), JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 3 ppm (13 mg/m3), short term exposure limit 6 ppm (26 mg/m3), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 6 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 6 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PERCHLORYL FLUORIDE-air 10 hour time-weighted average 3 ppm;
short term exposure limit 6 ppm 		NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)

Used as a fluorinating agent in chemical synthesis and as a liquid oxidant in rocket fuels

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