The Registry of Toxic Effects of Chemical Substances

Phosphorothioic acid, O - (2 - (ethylthio) ethyl) O,O - dimethyl ester

RTECS #: TG1650000

CAS #: 867-27-6

UPDATE: July 1997 MW: 230.30 MF: C6H15O3PS2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. REFERENCES:

SYNONYMS:

  1. O,O - Dimethyl - O - (2 - aethylthio - aethyl) monothiophosphat (German)
  2. O,O - Dimethyl O - ethylmercaptoethyl thiophosphate
  3. O,O - Dimethyl 2 - ethylmercaptoethyl thiophosphate, thiono isomer
  4. O,O - Dimethyl - O - (2 - ethyl - thio - ethyl) - monothiofosfaat (Dutch)
  5. O,O - Dimethyl O - 2 - (ethylthio) ethyl phosphorothioate
  6. O,O - Dimetil - O - (2 - etiltio - etil) - monotiofosfato (Italian)
  7. beta - Ethylmercaptoethyl dimethyl thionophosphate
  8. O - (2 - (Ethylthio) ethyl) O,O - dimethyl phosphorothioate
  1. 2 - (Ethylthio) ethyl dimethyl phosphorothionate
  2. Demeton - O - methyl
  3. Demeton - O - metile (Italian)
  4. Ethanol, 2 - (ethylthio) - , O - ester with O,O - dimethyl phosphorothioate
  5. Methyl - demeton - O
  6. O - Methyldemeton
  7. Thiophosphate de O,O - dimethyle et de O - 2 - ethylthio - ethyle (French)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
cat 		lowest published lethal concentration: 20 mg/m3 N/R GISAAA 28(3),21,1963
intravenous
rat 		lethal dose (50 percent kill): 216 mg/kg Behavioral: Muscle weakness

Behavioral: Ataxia

Lung, Thorax, or Respiration: Respiratory stimulation 		BIJOAK 67,187,1957
oral
cat 		lowest published lethal dose: 30 mg/kg N/R FATOAO 22,559,1959
oral
mouse 		lethal dose (50 percent kill): 46 mg/kg N/R FATOAO 22,559,1959
oral
rat 		lethal dose (50 percent kill): 75 mg/kg N/R FATOAO 22,559,1959
skin
rabbit 		lowest published lethal dose: 75 mg/kg Behavioral: Tremor FATOAO 22,559,1959


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
RREVAH 46,1,1973
TOXICOLOGY REVIEW
MZUZA8 (8),90,1973


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906-
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
MZUZA8 Meditsinskii Zhurnal Uzbekistana. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1957-
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-

Used as systemic insecticide and acaricide

RTECS Compound Description:
   Agricultural Chemical

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