The Registry of Toxic Effects of Chemical Substances

Propane, 1,2 - epoxy - 3 - (o - tolyoxy) -

RTECS #: TZ3700000

CAS #: 2210-79-9

UPDATE: March 1999 MW: 164.22 MF: C10H12O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Araldite DY 023
  2. O - Cresyl glycidyl ether
  3. 1,2 - Epoxy - 3 - (o - tolyloxy) propane
  4. Glycidyl o - methylphenyl ether
  5. Glycidyl 2 - methylphenyl ether
  6. Glycidyl o - tolyl ether
  1. o - Kresol - glycidaether (German)
  2. ( (2 - Methylphenoxy) methyl) oxirane
  3. 2 - ( (2 - Methylphenoxy) methyl) oxirane
  4. 2 - Methylphenyl glycidyl ether
  5. Oxirane, ( (2 - methylphenoxy) methyl) - (9CI)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		500 µL/24 hour severe NTIS** OTS0571540


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 33 µg/plate (+enzymatic activation step) MUREAV 172,105,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 6,090 mg/m3/4 hour Eye: Other eye effects

Lung, Thorax, or Respiration: Dyspnea

Skin and Appendages: Other: Hair 		NTIS** OTS0534658
oral
rat 		lethal dose (50 percent kill): 4 gm/kg N/R NTIS** OTS0571540
subcutaneous
mouse 		lethal dose (50 percent kill): 980 mg/kg N/R ARZNAD 15,1355,1965


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1680;
Number of Industries 7;
Total Number of Facilities 458;
Number of Occupations 11;
Total Number of Employees Exposed 7,077;
Total Number of Female Employees Exposed 1,430


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Drug
   Mutagen
   Primary Irritant

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