The Registry of Toxic Effects of Chemical Substances

Quaternary ammonium compounds, bis (hydrogenated tallow alkyl) dimethyl chlorides

RTECS #: UZ2997000

CAS #: 61789-80-8

UPDATE: September 2000 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Adogen 442
  2. Adogen 448
  3. Adogen 442 - 100 P
  4. Aliquat 264
  5. Ammonyx 2200
  6. Arquad 2HT
  7. Arquad 2HT75
  8. Ditallow dimethyl ammonium chloride
  1. Noramium M 2SH
  2. Noramium M 2SH15
  3. Prapagen WK
  4. Prapagen WKT
  5. Kemamine Q 9702C
  6. Kemamine qsml2
  7. Quaternium - 18


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 mg N/R ATDAEI 1,709,1992
skin
rabbit 		50 mg/21 day mild JACTDZ 1(2),71,1982


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 1,230 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Change in motor activity (specific assay) 		NTIS** OTS0537650
oral
dog 		lethal dose : >432 mg/kg N/R NTIS** OTS0543823
oral
mouse 		lethal dose : >576 mg/kg N/R NTIS** OTS0543823
oral
rat 		lethal dose (50 percent kill): >9,850 mg/kg N/R ATDAEI 1,708,1992


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 36,600 µg/kg/26 week- continuous Liver: Changes in liver weight NTIS** OTS0543811


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9305;
Number of Industries 29;
Total Number of Facilities 2,434;
Number of Occupations 31;
Total Number of Employees Exposed 39,266;
Total Number of Female Employees Exposed 7,513


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in cosmetics to maintain suspensions during application
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8786
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

Used in cosmetics to maintain suspensions during application

RTECS Compound Description:
   Primary Irritant

ALT CAS #: 60569-67-7
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