The Registry of Toxic Effects of Chemical Substances

Silicon

RTECS #: VW0400000

CAS #: 7440-21-3

UPDATE: November 2004 MW: 28.09 MF: Si


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Defoamer S - 10
  2. Polyeristalline silicon powder
  1. Silicon (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		3 mg mild FAONAU 53A,21,1974


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
rat 		lowest published lethal dose: 500 mg/kg Olfaction: Other olfaction effects

Eye: Other eye effects

Lung, Thorax, or Respiration: Respiratory stimulation 		NTIS** OTS0536164
oral
rat 		lethal dose (50 percent kill): 3,160 mg/kg N/R FAONAU 53A,21,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 10 mg/m3 DTLWS* 3,27,1973
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 10 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 10 mg/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 10 mg/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 4 mg/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m2, total inhalable dust, SEP2000
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 mg/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SILICON, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SILICON, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 68695;
Number of Industries 48;
Total Number of Facilities 3,856;
Number of Occupations 66;
Total Number of Employees Exposed 99,138
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4229;
Number of Industries 1;
Total Number of Facilities 12;
Number of Occupations 5;
Total Number of Employees Exposed 1,740;
Total Number of Female Employees Exposed 503
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4230;
Number of Industries 6;
Total Number of Facilities 118;
Number of Occupations 6;
Total Number of Employees Exposed 1,962;
Total Number of Female Employees Exposed 112
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X6495;
Number of Industries 1;
Total Number of Facilities 19;
Number of Occupations 2;
Total Number of Employees Exposed 2,379
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 68695;
Number of Industries 296;
Total Number of Facilities 59,062;
Number of Occupations 129;
Total Number of Employees Exposed 693,583;
Total Number of Female Employees Exposed 28,164


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in the synthesis of silanes and silicones and in manufacture of transistors
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

Used in the synthesis of silanes and silicones and in manufacture of transistors

NIOSH PROFILE (SILICON and ITS COMPOUNDS), SRI, 2/77

RTECS Compound Description:
   Primary Irritant

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