The Registry of Toxic Effects of Chemical Substances

Silicon carbide

RTECS #: VW0450000

CAS #: 409-21-2

UPDATE: May 2005 MW: 40.10 MF: CSi


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Annanox CK
  2. Betarundum
  3. Betarundum ST - S
  4. Betarundum UF
  5. Betarundum ultrafine
  6. Crystar
  7. Crystolon 37
  8. Crystolon 39
  9. Densic C 500
  10. DU - A 1
  11. DU - A 2
  12. DU - A 3
  13. DU - A 4
  14. DU - A 3C
  15. GC 10000
  16. SC 9
  17. SC 201
  18. SC 9 (Carbide)
  19. SCW 1
  20. SD - GP 6000
  21. SD - GP 8000
  1. Carbofrax M
  2. Carbolon
  3. Carbon silicide
  4. Carborundeum
  5. Carborundum
  6. Green densic
  7. Green densic GC 800
  8. Hitaceram SC 101
  9. KZ 3M
  10. KZ 5M
  11. KZ 7M
  12. Silicon carbide (ACGIH:OSHA)
  13. Silicon monocarbide
  14. Silundum
  15. Tokawhisker
  16. UA 1
  17. UA 2
  18. UA 3
  19. UA 4
  20. UF 15
  21. YE 5626


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
implant
rat 		lowest published toxic dose: 200 mg/kg Tumorigenic: Neoplastic by RTECS criteria

Tumorigenic: Tumors at site of application 		JJIND8 67,965,1981
intraperitoneal
rat 		lowest published toxic dose: 300 mg/kg/26 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Tumors 		EKSODD 11(2),13,1989


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intratracheal
rat 		lowest published toxic dose: 250 mg/kg Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Fibrosis (interstitial) 		VCVN1* -,357,1988
intratracheal
rat 		lowest published toxic dose: 8 mg/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other proteins 		TOLED5 145,273,2003


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 60 mg/m3/6 hour/13 week- intermittent Lung, Thorax, or Respiration: Changes in lung weight FAATDF 16,128,1991


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 ( intermittent,E) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 3 mg/m3 (R,E) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 f/cubic centimeter (F) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Suspected Human Carcinogen DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD NUISANCE PARTICULATES DTLWS* 3,28,1973
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 4 mg/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - FRANCE VME 10 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 4 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY (As Fibrous Dust): Carcinogen, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 4 mg/m3, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 4 mg/m3, respirable dust, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Suspected Human Carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Suspected Human Carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SILICON CARBIDE, resp. fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SILICON CARBIDE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 17525;
Number of Industries 184;
Total Number of Facilities 25,235;
Number of Occupations 97;
Total Number of Employees Exposed 268,082
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4228;
Number of Industries 4;
Total Number of Facilities 158;
Number of Occupations 12;
Total Number of Employees Exposed 8,693;
Total Number of Female Employees Exposed 84
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X6494;
Number of Industries 25;
Total Number of Facilities 1,250;
Number of Occupations 22;
Total Number of Employees Exposed 17,481;
Total Number of Female Employees Exposed 1,482
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 17525;
Number of Industries 129;
Total Number of Facilities 13,729;
Number of Occupations 97;
Total Number of Employees Exposed 250,945;
Total Number of Female Employees Exposed 19,568


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
EKSODD Eksperimental'naya Onkologiya. Experimental Oncology. (V/O Mezhdunarodnaya Kniga, 113095 Mosow, USSR) V.1- 1979-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

RTECS Compound Description:
   Tumorigen

ALT CAS #: 12504-67-5
ALT CAS #: 66039-27-8
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