The Registry of Toxic Effects of Chemical Substances

Thiophosphoryl chloride

RTECS #: XN2930000

CAS #: 3982-91-0

UPDATE: October 1997 MW: 169.38 MF: Cl3PS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Sulfidotrichlorid fosforecny (Czech)
  2. Thiophosphoric trichloride
  3. Fosforthiochlorid (Czech)
  4. Phosphorothioic trichloride
  5. Phosphorothionic trichloride
  6. Phosphorous sulfochloride
  1. Phosphorous thiochloride
  2. Phosphorous trichloride sulfide
  3. Thiochlorid fosforecny (Czech)
  4. Thiophosphoryl trichloride
  5. TL 262
  6. Trichlorophosphine sulfide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lethal concentration (50 percent kill): 400 mg/m3 Behavioral: Somnolence (general depressed activity)

Behavioral: Excitement 		GTPZAB 31(12),53,1987
inhalation
mouse 		lethal concentration (50 percent kill): 630 mg/m3 N/R GTPZAB 31(12),53,1987
inhalation
rat 		lethal concentration (50 percent kill): 20 ppm/4 hour N/R 28ZPAK -,17,1972
oral
guinea pig 		lethal dose (50 percent kill): 520 mg/kg N/R GTPZAB 31(12),53,1987
oral
mouse 		lethal dose (50 percent kill): 700 mg/kg N/R GTPZAB 31(12),53,1987
oral
rat 		lethal dose (50 percent kill): 660 mg/kg N/R GTPZAB 31(12),53,1987


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 2,925 mg/kg/90 day- intermittent Endocrine: Changes in adrenal weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases 		JJATDK 4,230,1984


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
AQMOAC #73-19,1973


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84222;
Number of Industries 1;
Total Number of Facilities 21;
Number of Occupations 2;
Total Number of Employees Exposed 62
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84222;
Number of Industries 2;
Total Number of Facilities 21;
Number of Occupations 14;
Total Number of Employees Exposed 1,944;
Total Number of Female Employees Exposed 187


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as intermediate
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
AQMOAC Air Quality Monographs. (Washington, DC) No.69-1 - No.75-25, 1969-75(?). Discontinued.
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-

Used as intermediate

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