The Registry of Toxic Effects of Chemical Substances

Titanium chloride (TiCl4)

RTECS #: XR1925000

CAS #: 7550-45-0

UPDATE: October 2002 MW: 189.70 MF: Cl4Ti


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Tetrachlorure de titane (French)
  2. Titaantetrachloride (Dutch)
  3. Titane (tetrachlorure de) (French)
  1. Titanio (tetracloruro di) (Italian)
  2. Titanium tetrachloride
  3. Titantetrachlorid (German)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lethal concentration (50 percent kill): 100 mg/m3/2 hour N/R 85GMAT -,111,1982
inhalation
rat 		lethal concentration (50 percent kill): 400 mg/m3 N/R 85GMAT -,111,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 10 mg/m3/6 hour/2 year- intermittent Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		TXAPA9 83,30,1986


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84219;
Number of Industries 3;
Total Number of Facilities 62;
Number of Occupations 9;
Total Number of Employees Exposed 1,337
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84219;
Number of Industries 3;
Total Number of Facilities 81;
Number of Occupations 5;
Total Number of Employees Exposed 2,107;
Total Number of Female Employees Exposed 131


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/98/101082/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in manufacture of TITANIUM metal and TITANIUM DIOXIDE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used in manufacture of TITANIUM metal and TITANIUM DIOXIDE

NIOSH PROFILE (TITANIUM AND ITS COMPOUNDS), SRC, 4/78

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