The Registry of Toxic Effects of Chemical Substances

Tungsten

RTECS #: YO7175000

CAS #: 7440-33-7

UPDATE: May 2004 MW: 183.85 MF: W


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. ACUTE TOXICITY DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Wolfram


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		500 mg/24 hour mild 28ZPAK -,19,1972
skin
rabbit 		500 mg/24 hour mild 28ZPAK -,19,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 1,210 µg/kg (35 week prior to copulation) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Specific developmental abnormalities: Musculoskeletal system 		GISAAA 42(8),30,1977
oral
rat 		lowest published toxic dose: 1,160 µg/kg (30 week prior to copulation/1-20 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system FATOAO 41,620,1978


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
rat 		lethal dose (50 percent kill): 5 gm/kg Vascular: Regional or general arteriolar or venous dilation

Liver: Other changes

Blood: Other changes 		INMEAF 15,482,1946


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1 mg/m3;short term exposure limit 3 mg/m3 DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 1 mg/m3 (soluble) DTLVS* 3,272,1971
Mine Safety and Health Administration (MSHA) STANDARD air-time-weighted average 5 mg/m3 (insoluble) DTLVS* 3,272,1971
Occupational Exposure Limit - DENMARK time-weighted average 5 mg/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 5 mg/m3, JAN1999
Occupational Exposure Limit - POLAND MAC(time-weighted average) fume and dust 5 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 2 mg/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 5 mg/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 5 mg( week)/m3, short term exposure limit 10 mg( week)/m3, SEP2000


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TUNGSTEN, insoluble-air time-weighted average 5 mg( week)/m3;
short term exposure limit 10 mg/m3 		NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TUNGSTEN, soluble-air 10 hour time-weighted average 1 mg( week)/m3;
short term exposure limit 3 mg/m3 		NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 74980;
Number of Industries 20;
Total Number of Facilities 530;
Number of Occupations 24;
Total Number of Employees Exposed 4,735
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X5928;
Number of Industries 4;
Total Number of Facilities 53;
Number of Occupations 11;
Total Number of Employees Exposed 3,907;
Total Number of Female Employees Exposed 1,258
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7685;
Number of Industries 5;
Total Number of Facilities 174;
Number of Occupations 15;
Total Number of Employees Exposed 4,822;
Total Number of Female Employees Exposed 3,021
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 74980;
Number of Industries 52;
Total Number of Facilities 1,623;
Number of Occupations 43;
Total Number of Employees Exposed 38,323;
Total Number of Female Employees Exposed 3,591


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in FERROUS and non-FERROUS alloys, and for filaments in incandescent lamps
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Tungsten (soluble and insoluble), 7074
OSHA ANALYTICAL METHOD #ID213


REFERENCES:

CODEN
REFERENCE
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
INMEAF Industrial Medicine. (Chicago, IL) V.1-18, 1932-49. For publisher information, see IOHSA5.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

Used in FERROUS and non-FERROUS alloys, and for filaments in incandescent lamps

RTECS Compound Description:
   Reproductive Effector
   Primary Irritant

 Click Here for Additional Information about RTECS