International Chemical Safety Cards 1,4-DIMETHOXYBENZENE ICSC: 1297 Benzene, 1,4-dimetoxy- Hydroquinone dimethyl ether p-Methoxyanisole C8H10O2 Molecular mass: 138.17 ICSC #    1297 CAS #     150-78-7 RTECS # CZ6650000 March 14, 2001 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. NO contact with combustibles. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE  •INHALATION Ventilation. Fresh air, rest.  •SKIN Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Remove all ignition sources. Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. (Extra personal protection: P1 filter respirator for inert particles.) Separated from strong oxidants. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1297 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 1,4-DIMETHOXYBENZENE ICSC: 1297 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: WHITE FLAKES , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. CHEMICAL DANGERS: Reacts with strong oxidants . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 212°C Melting point: 58-60°C Solubility in water: none Vapour pressure, kPa at 20°C: < 0.01 Flash point: 88°C Auto-ignition temperature: 438°C Explosive limits, vol% in air: 1.2-5.6 Octanol/water partition coefficient as log Pow: 2.04 ENVIRONMENTAL DATA N O T E S Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. ADDITIONAL INFORMATION ICSC: 1297 1,4-DIMETHOXYBENZENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.