NIOSH Pocket Guide to Chemical Hazards


CAS 75-45-6


RTECS PA6390000
Synonyms & Trade Names
Difluorochloromethane; Fluorocarbon-22; Freon® 22; Genetron® 22; Monochlorodifluoromethane; Refrigerant 22
DOT ID & Guide
1018 126


NIOSH REL: TWA 1000 ppm (3500 mg/m3) ST 1250 ppm (4375 mg/m3)
OSHA PEL†: none
IDLH N.D. See: IDLH INDEX Conversion 1 ppm = 3.54 mg/m3
Physical Description
Colorless gas with a faint, sweetish odor. [Note: Shipped as a liquefied compressed gas.]
MW: 86.5
BP: -41°F
FRZ: -231°F
Sol(77°F): 0.3%
VP: 9.4 atm
IP: 12.45 eV
RGasD: 3.11

Fl.P: NA

Nonflammable Gas
Incompatibilities & Reactivities
Alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc)
Measurement Methods
NIOSH 1018
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Frostbite
Eyes: Frostbite
Wash skin: No recommendation
Remove: No recommendation
Change: No recommendation
Provide: Frostbite wash
First Aid (See procedures)
Eye: Frostbite
Skin: Frostbite
Breathing: Respiratory support

Important additional information about respirator selection
Respirator Recommendations Not available.
Exposure Routes inhalation, skin and/or eye contact (liquid)
Symptoms Irritation respiratory system; confusion, drowsiness, ringing in ears; heart palpitations, cardiac arrhythmias; asphyxia; liver, kidney, spleen injury; liquid: frostbite
Target Organs respiratory system, cardiovascular system, central nervous system, liver, kidneys, spleen
See also: INTRODUCTION   See ICSC CARD: 0049