NIOSH Pocket Guide to Chemical Hazards

Ethylene glycol

CAS 107-21-1


RTECS KW2975000
Synonyms & Trade Names
1,2-Dihydroxyethane; 1,2-Ethanediol; Glycol; Glycol alcohol; Monoethylene glycol
DOT ID & Guide


NIOSH REL: See Appendix D
OSHA PEL†: none
IDLH N.D. See: IDLH INDEX Conversion
Physical Description
Clear, colorless, syrupy, odorless liquid. [antifreeze] [Note: A solid below 9°F.]
MW: 62.1
BP: 388°F
FRZ: 9°F
Sol: Miscible
VP: 0.06 mmHg
IP: ?

Sp.Gr: 1.11
Fl.P: 232°F
UEL: 15.3%
LEL: 3.2%

Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities
Strong oxidizers, chromium trioxide, potassium permanganate, sodium peroxide [Note: Hygroscopic (i.e., absorbs moisture from the air).]
Measurement Methods
NIOSH 5523; OSHA PV2024
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations Not available.
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, nose, throat; nausea, vomiting, abdominal pain, lassitude (weakness, exhaustion); dizziness, stupor, convulsions, central nervous system depression; skin sensitization
Target Organs Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0270