NIOSH Pocket Guide to Chemical Hazards

Trimellitic anhydride

CAS 552-30-7


RTECS DC2050000
Synonyms & Trade Names
1,2,4-Benzenetricarboxylic anhydride; 4-Carboxyphthalic anhydride; TMA; TMAN; Trimellic acid anhydride [Note: TMA is also a synonym for Trimethylamine.]
DOT ID & Guide


NIOSH REL: TWA 0.005 ppm (0.04 mg/m3) Should be handled in the workplace as an extremely toxic substance.
OSHA PEL†: none
IDLH N.D. See: IDLH INDEX Conversion 1 ppm = 7.86 mg/m3
Physical Description
Colorless solid.
MW: 192.1
BP: ?
MLT: 322°F
Sol: ?
VP: 0.000004 mmHg
IP: ?

Sp.Gr: ?
Fl.P: NA

Combustible Solid
Incompatibilities & Reactivities
None reported
Measurement Methods
NIOSH 5036; OSHA 98
See: NMAM or OSHA Methods
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations Not available.
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, nose, respiratory system; pulmonary edema, respiratory sensitization; rhinitis, asthma, cough, wheezing, dyspnea (breathing difficulty), malaise (vague feeling of discomfort), fever, muscle aches, sneezing
Target Organs Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0345